Heng Wu

Tianjin Medical University Cancer Institute and Hospital — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.9kcitations48works1.02yr avg
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Research Topics

MicroRNA in disease regulation(10), Epigenetics and DNA Methylation(6), Circular RNAs in diseases(6), Cellular Mechanics and Interactions(4), Cancer-related molecular mechanisms research(4)

Publications48 total

DOT1L Regulates Cellular Senescence during the Progression from Acute Kidney Injury to Chronic Kidney Disease via the microRNA-222-5p/WNT9B Signaling Pathway
American Journal of Nephrology·2025· 1 cited
Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes
Journal of Biological Chemistry·2023· 6 citedOpen Access
Disassembly of bundled F-actin and cellular remodeling via an interplay of Mical, cofilin, and F-actin crosslinkers
Proceedings of the National Academy of Sciences·2023· 15 citedOpen Access
Ang-(1–7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization
Cell & Bioscience·2023· 35 citedOpen Access
<scp>MiR</scp>‐192/<scp>NKRF</scp> axis confers lung cancer cell chemoresistance to cisplatin via the <scp>NF‐κB</scp> pathway
Thoracic Cancer·2021· 20 citedOpen Access
Bridging the Gap Between Morphometric Similarity Mapping and Gene Transcription in Alzheimer’s Disease
Frontiers in Neuroscience·2021· 13 citedOpen Access
Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
Nature Communications·2021· 35 citedOpen Access
Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders
Frontiers in Neuroscience·2021· 13 citedOpen Access
Enhanced Production of the Mical Redox Domain for Enzymology and F-actin Disassembly Assays
International Journal of Molecular Sciences·2021· 4 citedOpen Access
LncRNA H19 Promotes Cell Proliferation, Migration, and Angiogenesis of Glioma by Regulating Wnt5a/β-Catenin Pathway via Targeting miR-342
Cellular and Molecular Neurobiology·2020· 48 citedOpen Access
A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver
Proceedings of the National Academy of Sciences·2020· 55 citedOpen Access
Characterization of the promoter, downstream target genes and recognition DNA sequence of Mhy1, a key filamentation-promoting transcription factor in the dimorphic yeast Yarrowia lipolytica
Current Genetics·2019· 27 cited
Proteomics analysis of Schwann cell-derived exosomes: a novel therapeutic strategy for central nervous system injury
Molecular and Cellular Biochemistry·2019· 80 citedOpen Access
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes
Hepatology Communications·2019· 23 citedOpen Access
The MICALs are a Family of F-actin Dismantling Oxidoreductases Conserved from Drosophila to Humans
Scientific Reports·2018· 55 citedOpen Access
MicroRNA‐206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto‐oncogene and cyclin‐dependent kinase 6 in mice
Hepatology·2017· 75 citedOpen Access
Moesin Expression Is Associated with Glioblastoma Cell Proliferation and Invasion
Anticancer Research·2017· 37 citedOpen Access
The TORC1–Sch9–Rim15 signaling pathway represses yeast‐to‐hypha transition in response to glycerol availability in the oleaginous yeast <i>Yarrowia lipolytica</i>
Molecular Microbiology·2017· 18 citedOpen Access
MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis
Journal of Hepatology·2016· 100 citedOpen Access
Correction: Corrigendum: Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5
Nature Communications·2016· 184 citedOpen Access
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Frequent Co-authors

Jonathan R. Terman(7), Guisheng Song(5), Qinghua Zhou(5), Jimok Yoon(4), Clifford J. Steer(4), Li Y(4), Tianying Wang(4), Wenran Zhao(4), Q. Richard Lu(3), Ruei‐Jiun Hung(3), Yan Wang(3), Laurie L. Shekels(3), Jeffrey H. Albrecht(3), Zhaohua Zhong(3), Ying Li(3), Zhihao Wu(3), Ying Chen(2), Taehong Yang(2), Nidhi Gupta(2), Raymond Ng(2)