Joseph C. Wu

Cardiovascular Institute of the South — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

139h-index68.3kcitations1.2kworks9.52yr avg
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Research Topics

Pluripotent Stem Cells Research(351), Tissue Engineering and Regenerative Medicine(188), CRISPR and Genetic Engineering(159), Congenital heart defects research(119), 3D Printing in Biomedical Research(101)

Publications1.2k total

Somatic PIK3CA Activating Mutation in a Plexiform Lesion of a Patient With HHT and PAH
JACC Case Reports·2026Open Access
Multiscale profiling of tyrosine kinase inhibitor cardiotoxicity reveals mechanosensitive ion channel PIEZO1 as cardioprotective
Science Translational Medicine·2025
Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
Science Translational Medicine·2025
Galangin alleviates cardiac ischemia/reperfusion injury in human iPSC-derived cardiomyocytes and animal models
Journal of Molecular and Cellular Cardiology·2025
LabOS: The AI-XR Co-Scientist That Sees and Works With Humans
2025Open Access
Abstract 4354588: Unbiased Proteome of Human Myocardium and Serum Sampled at Sudden Death for Discovery of Biomarkers for Near-term Risk of Lethal Arrhythmia
Circulation·2025
Abstract 4363073: Somatic activating mutation in Phosphoinositide 3-kinase in a plexiform lesion of a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension
Circulation·2025
Molecular Mechanisms of Exosomes From Human iPSC‐Cardiomyocytes and Mesenchymal Stem Cells in Restoring the Injured Myocardium
Journal of the American Heart Association·2025Open Access
Deficiency of Smooth Muscle Adar1 Exacerbates Vascular Remodeling and Pulmonary Hypertension
Circulation Research·2025· 2 cited
Alternatives to animal testing are the future — it’s time that journals, funders and scientists embrace them
Nature·2025· 5 citedOpen Access
From one-size-fits-all to precision cardiovascular medicine
Frontiers in Science·2025Open Access
Age-related microbiome metabolites alter RNA splicing and chromatin accessibility in the brain
2025· 1 citedOpen Access
IGFBP2 Mediates Human iPSC-Cardiomyocyte Proliferation in a Cellular Contact-Dependent Manner
Circulation Research·2025Open Access
New Insights About Kidney Length in Pediatric ADPKD: Cross-Sectional Analysis of a Single-Center Cohort
Journal of the American Society of Nephrology·2025
Decoding long COVID-associated cardiovascular dysfunction: Mechanisms, models, and new approach methodologies
Journal of Molecular and Cellular Cardiology·2025· 2 cited
Generation of induced pluripotent stem cell lines from patients with thoracic aortic aneurysm carrying the ACTA2 gene mutation
Stem Cell Research·2025· 1 citedOpen Access
Generation of two induced pluripotent stem cell lines from Lynch syndrome patients carrying heterozygous MLH1 mutations
Stem Cell Research·2025Open Access
Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development
International Journal of Toxicology·2025Open Access
ACTL6A regulates the Warburg effect through coordinated activation of AP-1 signaling in head and neck squamous cell carcinoma
2025Open Access
Cardiac fibrosis: from mechanisms and models to medicines
Trends in Pharmacological Sciences·2025· 3 cited
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Frequent Co-authors

Robert C. Robbins(10), Shijun Hu(7), Kitchener D. Wilson(7), Ning Sun(7), Paul W. Burridge(5), Verónica Sánchez-Freire(5), Antje Ebert(4), Feng Lan(4), Oscar J. Abilez(4), Joseph Gold(4), Haodi Wu(4), Irving L. Weissman(4), Fangjun Jia(4), Michael T. Longaker(4), Patricia K. Nguyen(4), Donald M. Bers(4), Nazish Sayed(4), Sanjiv S. Gambhir(4), Elena Matsa(3), Jared M. Churko(3)