G. V. Shivashankar

Paul Scherrer Institute — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index7.8kcitations222works2.42yr avg
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Research Topics

Cellular Mechanics and Interactions(74), Genomics and Chromatin Dynamics(46), Nuclear Structure and Function(38), RNA Research and Splicing(31), Microtubule and mitosis dynamics(20)

Publications221 total

Identifying regulators of aged fibroblast activation in 3D tissue models
Repository for Publications and Research Data (ETH Zurich)·2025Open Access
Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells
Proceedings of the National Academy of Sciences·2025· 7 citedOpen Access
Author Correction: Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies
npj Precision Oncology·2025Open Access
Yielding behaviour of active particles in bulk and in confinement
Nature Physics·2025· 7 citedOpen Access
Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through <scp>ERK</scp> Signaling Pathway
Aging Cell·2025· 4 citedOpen Access
Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells
2025Open Access
Regulation of p65 nuclear localization and chromatin states by compressive force
Molecular Biology of the Cell·2025Open Access
Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts
Molecular Biology of the Cell·2024· 1 citedOpen Access
Correlative light and soft X-ray tomography of in situ mesoscale heterochromatin structure in intact cells
Scientific Reports·2024· 4 citedOpen Access
Compressive forces induce epigenetic activation of aged human dermal fibroblasts through ERK signaling pathway
2024· 1 citedOpen Access
Partially Shared Multi-Modal Embedding Learns Holistic Representation of Cell State
2024· 2 citedOpen Access
Chromatin Remodeling Due to Transient-Link-and-Pass Activity Enhances Subnuclear Dynamics
Physical Review Letters·2024· 3 cited
Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies
npj Precision Oncology·2023· 7 citedOpen Access
Adhesome Receptor Clustering is Accompanied by the Co- localization of the Associated Genes in the Cell Nucleus
2023Open Access
Transcriptional changes are tightly coupled to chromatin reorganization during cellular aging
Aging Cell·2023· 7 citedOpen Access
Yielding behaviour of active particles in bulk and in confinement
arXiv (Cornell University)·2023Open Access
Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing
Aging Cell·2023· 10 citedOpen Access
Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
Scientific Reports·2023· 4 citedOpen Access
Mechanical forces and the 3D genome
Current Opinion in Structural Biology·2023· 8 cited
Deleterious Mechanical Deformation Selects Mechanoresilient Cancer Cells with Enhanced Proliferation and Chemoresistance
Advanced Science·2023· 19 citedOpen Access
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Frequent Co-authors

Caroline Uhler(10), Yejun Wang(6), Saradha Venkatachalapathy(6), Doorgesh Sharma Jokhun(5), Aprotim Mazumder(5), Ekta Makhija(4), Karthik Damodaran(4), Mallika Nagarajan(4), Michael P. Sheetz(3), K. Venkatesan Iyer(3), Karren Yang(3), Anastasiya Belyaeva(3), Adityanarayanan Radhakrishnan(3), Abhishek Kumar(3), Dipanjan Bhattacharya(3), Alexander D. Bershadsky(2), Nikhil Jain(2), Farid Alisafaei(2), Vivek B. Shenoy(2), Marco Foiani(2)