Dirk Hauck

German Center for Infection Research — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index832citations31works2.02yr avg
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Research Topics

Bacterial biofilms and quorum sensing(13), Bacteriophages and microbial interactions(8), Glycosylation and Glycoproteins Research(7), Carbohydrate Chemistry and Synthesis(6), Antimicrobial Peptides and Activities(6)

Publications31 total

Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight <i>Pseudomonas aeruginosa</i>–<i>Burkholderia cenocepacia</i> Infections: A Biophysical Study
Journal of Medicinal Chemistry·2025· 2 citedOpen Access
The resuscitation-promoting factor (Rpf) from Micrococcus luteus and its putative reaction product 1,6-anhydro-MurNAc increase culturability of environmental bacteria
2023Open Access
The resuscitation-promoting factor (Rpf) from Micrococcus luteus and its putative reaction product 1,6-anhydro-MurNAc increase culturability of environmental bacteria
Access Microbiology·2023· 5 citedOpen Access
The resuscitation-promoting factor (Rpf) from Micrococcus luteus and its putative reaction product 1,6-anhydro-MurNAc increase culturability of environmental bacteria
2023Open Access
The resuscitation-promoting factor (Rpf) from Micrococcus luteus and its putative reaction product 1,6-anhydro-MurNAc increase culturability of environmental bacteria
2023Open Access
<i>Pseudomonas aeruginosa</i> <scp>LecB</scp> suppresses immune responses by inhibiting transendothelial migration
EMBO Reports·2023· 10 citedOpen Access
Neutralizing the Impact of the Virulence Factor LecA from <i>Pseudomonas aeruginosa</i> on Human Cells with New Glycomimetic Inhibitors
Angewandte Chemie International Edition·2022· 38 citedOpen Access
Neutralisation der Auswirkungen des Virulenzfaktors LecA aus <i>Pseudomonas aeruginosa</i> auf Humanzellen durch neue glykomimetische Inhibitoren
Angewandte Chemie·2022Open Access
A Remote Secondary Binding Pocket Promotes Heteromultivalent Targeting of DC-SIGN
Journal of the American Chemical Society·2021· 31 citedOpen Access
Optimized Henry Reaction Conditions for the Synthesis of an l-Fucose C-Glycosyl Derivative
2021· 2 cited
Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of <i>Pseudomonas aeruginosa</i>
Journal of Medicinal Chemistry·2020· 43 citedOpen Access
Anti-biofilm Agents against <i>Pseudomonas aeruginosa</i>: A Structure–Activity Relationship Study of <i>C</i>-Glycosidic LecB Inhibitors
Journal of Medicinal Chemistry·2019· 70 citedOpen Access
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of <i>Pseudomonas aeruginosa</i>
Journal of the American Chemical Society·2017· 177 citedOpen Access
Photorhabdus luminescens lectin A (PllA): A new probe for detecting α-galactoside–terminating glycoconjugates
Journal of Biological Chemistry·2017· 17 citedOpen Access
Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging
Angewandte Chemie·2017· 14 citedOpen Access
Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging
Angewandte Chemie International Edition·2017· 73 citedOpen Access
Efficient Two Step β‐Glycoside Synthesis from <i>N</i> ‐Acetyl <scp>d</scp> ‐Glucosamine: Scope and Limitations of Copper(II) Triflate‐Catalyzed Glycosylation
ChemistrySelect·2017· 11 citedOpen Access
<i>O</i>-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-<i>O</i>-methyl-L-selenofucopyranoside
Beilstein Journal of Organic Chemistry·2016· 7 citedOpen Access
Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa
Organic & Biomolecular Chemistry·2016· 55 cited
Development of a competitive binding assay for the <i>Burkholderia cenocepacia</i> lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors
MedChemComm·2016· 24 cited
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Frequent Co-authors

Alexander Titz(28), Anne Imberty(13), Roman Sommer(11), Annabelle Varrot(11), Stefanie Wagner(7), Ines Joachim(6), Katharina Rox(4), Juan Guzman(4), Dipansi Raval(4), Anja Poehlein(4), Thomas Degenkolb(4), Rolf Daniel(4), Andreas Vilcinskas(4), Benjamin Frommeyer(3), Bodo Philipp(3), Heiko M. Möller(3), Thomas E. Exner(3), Joscha Meiers(3), Eva Zahorska(3), Émilie Gillon(3)