Michaela Kneissel

Novartis (Switzerland) — Switzerland

Medicine · Health Sciences

46h-index9.4kcitations130works1.32yr avg
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Research Topics

Bone health and osteoporosis research(40), Bone Metabolism and Diseases(37), Bone health and treatments(36), Connective tissue disorders research(14), Wnt/β-catenin signaling in development and cancer(12)

Publications130 total

Communication is Key: Using Complex Co‐cultures to Decipher the Intercellular Crosstalk that Drives AD
Alzheimer s & Dementia·2025Open Access
Discovery and Characterization of Zilurgisertib, a Potent and Selective Inhibitor of Activin Receptor-like Kinase-2 (ALK2) for the Treatment of Fibrodysplasia Ossificans Progressiva
ACS Medicinal Chemistry Letters·2025
Exercise-Induced Myostimulin Enhances Muscle Function in Health and Disease
2025
Characterization of quinazolinone calcilytic therapy for autosomal dominant hypocalcemia type 1 (ADH1)
Journal of Biological Chemistry·2025· 2 citedOpen Access
Targeting the IL-17A pathway for therapy in early-stage tendinopathy
RMD Open·2025· 3 citedOpen Access
Combined physical and pharmacological anabolic osteoporosis therapies increase bone response and mechanoregulation in female mice
2024· 3 citedOpen Access
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
Calcified Tissue International·2023· 3 cited
Inhibiting WNT secretion reduces high bone mass caused by Sost loss-of-function or gain-of-function mutations in Lrp5
Bone Research·2023· 13 citedOpen Access
Inhibiting Wnt Secretion Reduces High Bone Mass Caused by Sost Deficiency or Point Mutations in Lrp5
2023· 1 citedOpen Access
Angiopoietin-like 3-derivative LNA043 for cartilage regeneration in osteoarthritis: a randomized phase 1 trial
Nature Medicine·2022· 59 citedOpen Access
LNA043 A NOVEL CANDIDATE FOR OSTEOARTHRITIS TREATMENT INDUCES CARTILAGE REGENERATION AND REVERSES THE OSTEOARTHRITIS TRANSCRIPTOME
Osteoarthritis and Cartilage·2022
Cortical bone adaptation to a moderate level of mechanical loading in male Sost deficient mice
Scientific Reports·2020· 17 citedOpen Access
Effects of Long-Term Sclerostin Deficiency on Trabecular Bone Mass and Adaption to Limb Loading Differ in Male and Female Mice
Calcified Tissue International·2019· 21 cited
Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space
Scientific Reports·2019· 56 citedOpen Access
Systemic sclerostin antibody treatment increases osseointegration and biomechanical competence of zoledronic-acid-coated dental implants in a rat osteoporosis model
European Cells and Materials·2019· 24 citedOpen Access
P082/O24 Sclerostin deficiency affects RANKL-mediated osteoclast differentiation
Annals of the Rheumatic Diseases·2019Open Access
Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume
Calcified Tissue International·2018· 10 cited
<i>Sost</i> deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched <i>in vivo</i> loading experiments in mice
Journal of The Royal Society Interface·2018· 9 citedOpen Access
P081 Sclerostin affects rankl-mediated osteoclast differentiation
Annals of the Rheumatic Diseases·2018Open Access
Tough Composite Hydrogels with High Loading and Local Release of Biological Drugs
Advanced Healthcare Materials·2018· 78 citedOpen Access
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Frequent Co-authors

Ina Krämer(22), H. J. Keller(8), Christine Halleux(7), Olivier Leupin(4), A. Boyde(4), Mira Šuša(4), Paul Roschger(4), Gabriela G. Loots(3), Brigitte Fournier(3), Anne Studer(3), Michelle M. McDonald(3), Klaus Seuwen(3), Ming-Kang Chang(3), Sabine Guth(3), Jonathan H. Gooi(2), Patrick Matthias(2), Myma Baptist(2), Nicole M. Collette(2), Frédéric Morvan(2), Michaela R. Reagan(2)