Jianhang Jia

University of Kentucky — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index4.2kcitations49works0.02yr avg
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Research Topics

Hedgehog Signaling Pathway Studies(33), Developmental Biology and Gene Regulation(17), Epigenetics and DNA Methylation(17), Ocular Disorders and Treatments(9), Wnt/β-catenin signaling in development and cancer(6)

Publications49 total

Neurotensin inhibits AMPK activity and concurrently enhances FABP1 expression in small intestinal epithelial cells associated with obesity and aging
Experimental & Molecular Medicine·2025Open Access
Phosphatidic acid binding to Patched contributes to the inhibition of Smoothened and Hedgehog signaling in<i>Drosophila</i>wing development
Science Signaling·2023Open Access
Regulation of Smoothened Trafficking and Abundance in Hedgehog Signaling
Frontiers in Cell and Developmental Biology·2022· 3 citedOpen Access
Characterization of Smoothened Phosphorylation and Activation
Methods in molecular biology·2021· 2 citedOpen Access
Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner
Cellular and Molecular Gastroenterology and Hepatology·2021· 22 citedOpen Access
Mechanisms of Smoothened Regulation in Hedgehog Signaling
Cells·2021· 43 citedOpen Access
Absence of neurotensin attenuates intestinal dysbiosis and inflammation by maintaining Mmp7/α‐defensin axis in diet‐induced obese mice
The FASEB Journal·2020· 19 citedOpen Access
Hedgehog signaling promotes lipolysis in adipose tissue through directly regulating Bmm/ATGL lipase
Developmental Biology·2019· 28 citedOpen Access
Su1204 - NTR3 Interacts with NTR1 to Extend the Duration of Neurotensin Signaling
Gastroenterology·2018
An intracellular activation of Smoothened that is independent of Hedgehog stimulation in <i>Drosophila</i>
Journal of Cell Science·2018· 26 citedOpen Access
Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice
Stem Cell Reports·2017· 27 citedOpen Access
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation
Nature Communications·2017· 131 citedOpen Access
SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling
Scientific Reports·2017· 20 citedOpen Access
Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination
PLoS Genetics·2016· 25 citedOpen Access
An obligatory role for neurotensin in high-fat-diet-induced obesity
Nature·2016· 251 citedOpen Access
PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail
PLoS Biology·2016· 77 citedOpen Access
Smoothened regulation in response to Hedgehog stimulation
Frontiers in Biology·2015· 12 citedOpen Access
Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling
Molecular and Cellular Biology·2015· 82 citedOpen Access
PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation
PLoS Pathogens·2015· 119 citedOpen Access
Analysis of Smoothened Phosphorylation and Activation in Cultured Cells and Wing Discs of Drosophila
Methods in molecular biology·2015· 1 cited
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Frequent Co-authors

Jin Jiang(17), Yajuan Liu(15), Kai Jiang(11), Tianyan Gao(7), B. Mark Evers(7), Chao Tong(6), Junkai Fan(6), Yajuan Liu(5), Chi Wang(5), Bing Wang(4), Haining Zhu(4), Heidi L. Weiss(4), Hongge Jia(4), Jie Zhang(4), Kazuhito Amanai(3), Yun Zhao(3), Ruohan Xia(3), Tianxin Yu(3), Bing Wang(2), Gelin Wang(2)