Chamelli Jhappan

National Institute on Aging — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index3.6kcitations27works0.02yr avg
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Research Topics

Virus-based gene therapy research(6), Animal Genetics and Reproduction(6), DNA Repair Mechanisms(3), Cancer-related Molecular Pathways(3), CRISPR and Genetic Engineering(3)

Publications26 total

Strategies to Prevent or Remediate Cancer and Treatment-Related Aging
JNCI Journal of the National Cancer Institute·2020· 99 citedOpen Access
Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors
JNCI Journal of the National Cancer Institute·2019· 209 citedOpen Access
TGFβ1 and TGFα contrarily affect alveolar survival and tumorigenesis in mouse mammary epithelium
International Journal of Cancer·2006· 7 cited
Ultraviolet radiation and cutaneous malignant melanoma
Oncogene·2003· 277 cited
Erratum: Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis (Nature Medicine (2002) 8 (1276-1280))
2003· 5 cited
Erratum: Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
Nature Medicine·2003Open Access
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
Proceedings of the National Academy of Sciences·2002· 346 citedOpen Access
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
Nature Medicine·2002· 157 cited
The p53 Response to DNA Damage In Vivo Is Independent of DNA-Dependent Protein Kinase
Molecular and Cellular Biology·2000· 51 citedOpen Access
Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation
Proceedings of the National Academy of Sciences·1998· 87 citedOpen Access
DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus
Nature Genetics·1997· 143 cited
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
PubMed·1996· 175 cited
Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells.
PubMed·1995· 62 cited
Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development.
PubMed·1995· 98 cited
Ectopic TGFβ1 Expression in the Secretory Mammary Epithelium Induces Early Senescence of the Epithelial Stem Cell Population
Developmental Biology·1995· 180 cited
Transgenic mice provide genetic evidence that transforming growth factor alpha promotes skin tumorigenesis via H-ras-dependent and H-ras-independent pathways.
PubMed·1994· 37 cited
An Epidermal Growth Factor Receptor Promoter Construct Selectively Expresses in the Thymus and Spleen of Transgenic Mice
Cellular Immunology·1993· 2 cited
Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.
The EMBO Journal·1993· 223 citedOpen Access
TGFα Induced Proliferative Changes in Transgenic Mice
1993
Hypertrophic gastropathy resembling Ménétrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach.
Journal of Clinical Investigation·1992· 140 citedOpen Access
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Frequent Co-authors

Glenn Merlino(17), Gilbert H. Smith(9), Richard Sharp(6), C Stahle(4), Edith C. Kordon(4), Miriam R. Anver(4), Daniel Gallahan(3), Robert Callahan(3), Lothar Hennighausen(3), Juan A. Recio(3), Ronald A. DePinho(3), George F. Vande Woude(3), Jennifer Guida(2), Tim A. Ahles(2), Judith Campisi(2), Rebecca Fuldner(2), Lisa Gallicchio(2), Paige Green(2), Ronald A. Kohanski(2), Kirsten K. Ness(2)