Isabella Screpanti

Sapienza University of Rome — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

65h-index13.3kcitations252works0.82yr avg
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Research Topics

Hedgehog Signaling Pathway Studies(41), Epigenetics and DNA Methylation(40), Developmental Biology and Gene Regulation(24), Immune Cell Function and Interaction(22), Cancer-related gene regulation(21)

Publications252 total

MAML1 drives Notch and Hedgehog oncogenic pathways by inhibiting Itch activity in triple-negative breast cancer
Cell Death and Differentiation·2025Open Access
Harris Hawks optimization based deep learning models for heart disease diagnosis
Scientific Reports·2025Open Access
Optimized Machine Learning Model using Binary Grasshopper Algorithm for Heart Disease Diagnosis
2025
An Enhanced Approach to Identify and Classify Heart Disease using Machine Learning Models
2025
T cell biology drives the efficacy and toxicity of post-transplant cyclophosphamide in graft-versus-host disease prophylaxis
immuneACCESS·2024
The NF-κB1/p50 Subunit Influences the Notch/IL-6-Driven Expansion of Myeloid-Derived Suppressor Cells in Murine T-Cell Acute Lymphoblastic Leukemia
International Journal of Molecular Sciences·2024· 1 citedOpen Access
Correction: Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL
Oncogene·2024Open Access
Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL
Oncogene·2024· 5 citedOpen Access
Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL
Research Square (Research Square)·2023Open Access
Data from Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance
2023Open Access
Data from Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance
2023Open Access
Supplementary Data from Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance
2023Open Access
Supplementary Data from Kras/ADAM17-Dependent Jag1-ICD Reverse Signaling Sustains Colorectal Cancer Progression and Chemoresistance
2023Open Access
Data from Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy
2023Open Access
Supplementary Methods, Figures 1-7, Table 1 from Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy
2023Open Access
Supplementary Methods, Figures 1-7, Table 1 from Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy
2023Open Access
Data from Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy
2023Open Access
Loss of <scp>ATP2C1</scp> function promotes trafficking and degradation of <scp>NOTCH1</scp>: Implications for Hailey‐Hailey disease
Experimental Dermatology·2023· 3 citedOpen Access
Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL
Cancers·2022· 9 citedOpen Access
GSK3β is a critical, druggable component of the network regulating the active NOTCH1 protein and cell viability in CLL
Cell Death and Disease·2022· 8 citedOpen Access
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Frequent Co-authors

Alberto Gulino(33), Elisabetta Ferretti(14), Enrico De Smaele(14), Lucia Di Marcotullio(14), Diana Bellavia(12), Luigi Frati(12), Gianluca Canettieri(9), Alessandra Vacca(9), Saula Checquolo(8), Antonio Francesco Campese(8), Evelina Miele(7), Agnese Pò(7), Sonia Coni(7), Giuseppe Giannini(7), María Pía Felli(7), Paola Infante(6), Marella Maroder(6), Azzura Greco(5), Carlo Capalbo(4), Emanuela Rosati(4)