Jonathan Larkin

GlaxoSmithKline (United States) — United States

Medicine · Health Sciences

26h-index2.3kcitations68works5.62yr avg
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Research Topics

Osteoarthritis Treatment and Mechanisms(41), Inflammatory mediators and NSAID effects(20), Rheumatoid Arthritis Research and Therapies(14), Hepatitis B Virus Studies(6), Total Knee Arthroplasty Outcomes(6)

Publications67 total

Rapidly progressive osteoarthritis (RPOA) in companion animals treated with bedinvetmab (Librela™): an expected pathophysiological phenomenon or a cause for concern?
Frontiers in Veterinary Science·2025Open Access
CYTOKINE PROFILING OF MOLECULAR SUBGROUPS OF KNEE OSTEOARTHRITIS PATIENTS FROM THE APPROACH COHORT
Osteoarthritis and Cartilage·2025
Serum immunoassays identify Cartilage Acidic Protein 1 (CRTAC1) as a biomarker of osteoarthritis
Osteoarthritis and Cartilage·2025
IDENTIFICATION OF PROTEOMIC BIOMARKERS FOR PREDICTING OSTEOARTHRITIS PROGRESSION: DATA FROM THE IMI-APPROACH COHORT
Osteoarthritis and Cartilage·2025
Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease
Matrix Biology·2024· 11 citedOpen Access
Longitudinal stability of molecular endotypes of knee osteoarthritis patients
Osteoarthritis and Cartilage·2024· 6 citedOpen Access
Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development
Matrix Biology·2024· 9 citedOpen Access
LONGITUDINAL STABILITY OF MOLECULAR ENDOTYPES OF KNEE OSTEOARTHRITIS PATIENTS FROM THE APPROACH COHORT
Osteoarthritis and Cartilage·2024Open Access
From biochemical markers to molecular endotypes of osteoarthritis: a review on validated biomarkers
Expert Review of Molecular Diagnostics·2024· 24 citedOpen Access
Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study
Osteoarthritis and Cartilage Open·2023· 7 citedOpen Access
Animal Models of Osteoarthritis Part 1–Preclinical Small Animal Models: Challenges and Opportunities for Drug Development
Current Protocols·2022· 19 citedOpen Access
OP0224 DISCOVERY PROTEOMICS ANALYSIS IN THE IMI-APPROACH COHORT SHOWS THE DIFFERENTIAL MODULATION AT 24 MONTHS OF PROTEIN PROFILES ASSOCIATED WITH STRUCTURAL OR PAIN PROGRESSION IN OSTEOARTHRITIS
Annals of the Rheumatic Diseases·2022Open Access
The association of the lipid profile with knee and hand osteoarthritis severity: the IMI-APPROACH cohort
Osteoarthritis and Cartilage·2022· 23 citedOpen Access
Predicted and actual 2-year structural and pain progression in the IMI-APPROACH knee osteoarthritis cohort
Lara D. Veeken·2022· 11 citedOpen Access
Correction to: Making the patient voice heard in a research consortium: experiences from an EU project (IMI-APPROACH)
Research Involvement and Engagement·2022· 2 citedOpen Access
DISCOVERY OF OSTEOARTHRITIS ENDOTYPES VIA CLUSTERING OF BIOCHEMICAL MARKER DATA IN THE IMI-APPROACH COHORT
Osteoarthritis and Cartilage·2022· 1 cited
THE ASSOCIATION OF THE LIPID PROFILE WITH KNEE AND HAND OSTEOARTHRITIS SEVERITY: THE IMI-APPROACH COHORT
Osteoarthritis and Cartilage·2022· 2 cited
Osteoarthritis endotype discovery via clustering of biochemical marker data
Annals of the Rheumatic Diseases·2022· 140 citedOpen Access
Cherry Jezebel
2022
Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping
RMD Open·2021· 32 citedOpen Access
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Frequent Co-authors

Ali Mobasheri(21), Anne‐Christine Bay‐Jensen(18), C. Ladel(16), M. Kloppenburg(11), Harrie Weinans(11), Francisco J. Blanco(10), I.K. Haugen(10), Francis Bérenbaum(9), Jaume Bacardit(8), John Loughlin(8), Alain Lalande(7), A.C. Marijnissen(7), Yves Henrotin(6), Paco M J Welsing(6), M. Loef(6), W.E. van Spil(5), Paweł Widera(5), André Struglics(5), M.A. Karsdal(5), Marc C. Levesque(4)