Lucas A. Horn

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

22h-index2.4kcitations98works1.22yr avg
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Research Topics

Immune cells in cancer(41), Immune Cell Function and Interaction(31), Cancer Immunotherapy and Biomarkers(28), Immunotherapy and Immune Responses(17), Advanced Glycation End Products research(16)

Publications98 total

Abstract B019: Inhibition of the CXCR1 and CXCR2 chemokine receptors synergizes with docetaxel to remodel the tumor-immune microenvironment and effectively control tumor growth
Cancer Research·2026
Abstract A018: Characterization of the anti-tumor efficacy of memory cytokine enriched NK cells against tumors with neuroendocrine features
Cancer Immunology Research·2026
Abstract B021: Modeling Human Immune Competent Patient-Derived Metastatic Prostate Cancer in Vivo
Cancer Research·2026
647 Selective targeting of integrins a <sub>v</sub> b <sub>8</sub> and a <sub>v</sub> b <sub>1</sub> improves anti-tumor responses mediated by immune checkpoint inhibition
Regular and Young Investigator Award Abstracts·2025Open Access
623 Docetaxel synergizes with inhibition of the chemokine receptors CXCR1 and CXCR2 for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer models
Regular and Young Investigator Award Abstracts·2025Open Access
Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer models
Journal of Experimental & Clinical Cancer Research·2024· 7 citedOpen Access
804 Anti-tumor effect of a novel Vβ TCR-targeting bifunctional agent in combination with anti-PD1 in checkpoint refractory murine lung cancer models
Regular and Young Investigator Award Abstracts·2023Open Access
1136 Vaccine targeting of the tumor-associated antigen brachyury reduces development of colitis-induced colorectal lesions in the APC<sup>Min/+</sup>mouse model
Regular and Young Investigator Award Abstracts·2023Open Access
358 Characterization of the anti-tumor activity of memory cytokine enriched NK cells against tumors with neuroendocrine features
Regular and Young Investigator Award Abstracts·2023Open Access
Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis
Journal for ImmunoTherapy of Cancer·2023· 7 citedOpen Access
Data from A Soluble Form of CD80 Enhances Antitumor Immunity by Neutralizing Programmed Death Ligand-1 and Simultaneously Providing Costimulation
2023Open Access
Supplementary Figure 1 from A Soluble Form of CD80 Enhances Antitumor Immunity by Neutralizing Programmed Death Ligand-1 and Simultaneously Providing Costimulation
2023Open Access
Data from Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes
2023Open Access
Data from A Soluble Form of CD80 Enhances Antitumor Immunity by Neutralizing Programmed Death Ligand-1 and Simultaneously Providing Costimulation
2023Open Access
Supplementary Figure 1 from A Soluble Form of CD80 Enhances Antitumor Immunity by Neutralizing Programmed Death Ligand-1 and Simultaneously Providing Costimulation
2023Open Access
Supplementary Figures 1 and 2 from Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes
2023Open Access
Data from Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes
2023Open Access
Supplementary Figures 1 and 2 from Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes
2023Open Access
Supplementary Figure S7 from Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models
2023Open Access
Supplementary Figure S4 from Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models
2023Open Access
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Frequent Co-authors

Suzanne Ostrand‐Rosenberg(23), Claudia Palena(22), Jeffrey Schlom(17), Virginia K. Clements(14), Katherine H. Parker(13), Pratima Sinha(12), Kristen Fousek(11), Dean Y. Maeda(11), John A. Zebala(11), Kevin J. Tracey(10), Jianhua Li(9), Clint Allen(8), Sarah Greene(7), Yvette Robbins(7), Jay Friedman(7), Paúl E. Clavijo(7), Wojciech K. Mydlarz(6), Angel P. Huynh(6), Nicole C. Schmitt(6), Haiyan Qin(6)