Guochao Liao

Guangzhou University of Chinese Medicine — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.8kcitations76works3.32yr avg
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Research Topics

Glycosylation and Glycoproteins Research(12), Immunotherapy and Immune Responses(11), Carbohydrate Chemistry and Synthesis(11), Epigenetics and DNA Methylation(7), SARS-CoV-2 and COVID-19 Research(6)

Publications76 total

Nanoclay-Triggered In Situ Self-Gelling Yam Microparticles via Coagulation Activation for Robust Wet Tissue Adhesion and Instant Hemostasis
ACS Applied Materials & Interfaces·2025
A customized immunomodulator reinforces the T cell-mediated immunological cascade for cancer therapy
Chemical Engineering Journal·2025
Optimization, Immunological Evaluation, and Combination Study of Mincle-Dependent Self-Adjuvanted Anti-Tn Cancer Vaccines with an External Adjuvant
Journal of Medicinal Chemistry·2025· 1 cited
Structure-based optimization of isoaurostatin as novel PDE4 inhibitors with anti-fibrotic effects
Chinese Chemical Letters·2024· 2 cited
New Processes for Ionizing Nonvolatile Compounds in Mass Spectrometry: The Road of Discovery to Current State-of-the-Art
Journal of the American Society for Mass Spectrometry·2024· 3 citedOpen Access
Fully Synthetic TF-Based Self-Adjuvanting Vaccine Simultaneously Triggers iNKT Cells and Mincle and Protects Mice against Tumor Development
Journal of Medicinal Chemistry·2024· 6 cited
Design, Synthesis, and Bioactivity Evaluation of a TF-Based Cancer Vaccine Candidate Using Lipid A Mimetics As a Built-In Adjuvant
Journal of Medicinal Chemistry·2024· 2 cited
Mitochondria-targeted carrier-free nanoparticles based on dihydroartemisinin against hepatocellular carcinoma
Chinese Chemical Letters·2024· 12 cited
Design, synthesis and biological evaluation of the positional isomers of the galactose conjugates able to target hepatocellular carcinoma cells via ASGPR-mediated cellular uptake and cytotoxicity
European Journal of Medicinal Chemistry·2023· 18 cited
Assessment of Purity, Stability, and Pharmacokinetics of NGP-1, a Novel Prodrug of GS441254 with Potential Anti-SARS-CoV-2 Activity, Using Liquid Chromatography
Molecules·2023· 2 citedOpen Access
Discovery of new tetrahydroisoquinolines as potent and selective LSD1 inhibitors for the treatment of MLL-rearranged leukemia
European Journal of Medicinal Chemistry·2023· 3 citedOpen Access
Single-dose rAAV5-based vaccine provides long-term protective immunity against SARS-CoV-2 and its variants
Virology Journal·2022· 14 citedOpen Access
Design, synthesis and immunological evaluation of monophosphoryl lipid A derivatives as adjuvants for a RBD-hFc based SARS-CoV-2 vaccine
RSC Medicinal Chemistry·2022· 2 citedOpen Access
Human Fc-Conjugated Receptor Binding Domain-Based Recombinant Subunit Vaccines with Short Linker Induce Potent Neutralizing Antibodies against Multiple SARS-CoV-2 Variants
Vaccines·2022· 3 citedOpen Access
Fully synthetic Tn-based three-component cancer vaccine using covalently linked TLR4 ligand MPLA and iNKT cell agonist KRN-7000 as built-in adjuvant effectively protects mice from tumor development
Acta Pharmaceutica Sinica B·2022· 30 citedOpen Access
MUC1 vaccines using β-cyclodextrin grafted chitosan (CS-g-CD) as carrier via host-guest interaction elicit robust immune responses
Chinese Chemical Letters·2022· 17 cited
β-1,2-Mannan-based glycoconjugates as potential antifungal vaccines
Chinese Chemical Letters·2021· 5 cited
Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice
Acta Pharmacologica Sinica·2021· 8 citedOpen Access
Synthesis and Biological Activities of Diosgenin-Triazole Conjugates with a 1,3-Dipolar Cycloaddition Reaction
Chemistry of Natural Compounds·2021
Single-shot rAAV5-based Vaccine Provides Long-term Protective Immunity against SARS-CoV-2 and Its Variants
2021· 1 cited
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Frequent Co-authors

Zhongqiu Liu(13), Zhongwu Guo(13), Zhifang Zhou(11), Zhiqiang Yu(7), Deying Yang(7), Bin Yu(6), Yi Cao(5), Yuan Fang(4), Leilei Ma(4), Yanhuai Ding(4), Xiaoxiao Qi(4), Qinghai Lian(4), Lingqiang Gao(4), Xiang Luo(4), Qiling Chen(3), Liming Zeng(3), Satadru Sekhar Mandal(3), Mohabul A. Mondal(3), Wenwei Li(3), Peng Wu(3)