Syed A. Mian

King's College London — United Kingdom

Medicine · Health Sciences

21h-index2.1kcitations55works2.32yr avg
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Research Topics

Acute Myeloid Leukemia Research(31), Hematopoietic Stem Cell Transplantation(16), Myeloproliferative Neoplasms: Diagnosis and Treatment(9), Mesenchymal stem cell research(6), Lymphoma Diagnosis and Treatment(5)

Publications55 total

Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny
Blood Cancer Discovery·2025Open Access
Mesenchymal stromal cells from <i>JAK2</i> <sup> <i>V617F</i> </sup> myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo
HemaSphere·2025Open Access
A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression
Nature Communications·2025· 2 citedOpen Access
Fetal‐hemoglobin‐expressing red blood cells (“F cells”) consist of three distinct types as revealed by single‐cell transcriptomic analysis of circulating reticulocytes
HemaSphere·2025Open Access
Is the bone marrow microenvironment the hidden catalyst in malignant haematopoiesis?
Leukemia·2025· 1 citedOpen Access
Influence of donor–recipient sex on engraftment of normal and leukemia stem cells in xenotransplantation
HemaSphere·2024· 11 citedOpen Access
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in <i>SF3B1</i> -mutated myelodysplasia
Science Translational Medicine·2023· 28 citedOpen Access
Characterization of the Human Mesenchymal Stromal Compartment in Normal Homeostasis and Acute Myeloid Leukemia at the Level of the Single Cell
Blood·2022
Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population
Nature Communications·2022· 46 citedOpen Access
Vitamin B5 and Succinyl-CoA Improve Ineffective Erythropoiesis in SF3B1 Mutated Myelodysplasia
Blood·2021· 3 cited
Nature or Nurture? Role of the Bone Marrow Microenvironment in the Genesis and Maintenance of Myelodysplastic Syndromes
Cancers·2021· 21 citedOpen Access
Engraftment of Human Hematopoietic Cells in Biomaterials Implanted in Immunodeficient Mouse Models
Methods in molecular biology·2021· 2 cited
Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem Cells
Blood Cancer Discovery·2020· 36 citedOpen Access
Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction
Blood·2020· 25 citedOpen Access
Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction: Mechanism of Treg depletion in AA
2020
Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7
Leukemia·2020· 17 citedOpen Access
Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study
The Lancet Haematology·2019· 55 cited
Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches
The Journal of Experimental Medicine·2018· 120 citedOpen Access
BCR-ABL1 kinase domain mutation screening using next generation sequencing in CML and Ph plus ALL patients
Oxford University Research Archive (ORA) (University of Oxford)·2018
Bone Marrow Stem Cells from Patients with Myelodysplastic Syndrome (MDS) Engraft and Migrate in-between the Humanized Niches in Immuno-Compromised Mouse Models
2017· 1 cited
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Frequent Co-authors

Ghulam J. Mufti(27), Austin Kulasekararaj(25), Alexander Smith(25), Dominique Bonnet(20), Azim Mohamedali(15), Joop Gäken(12), Judith Marsh(12), Kevin Rouault‐Pierre(10), Nicholas Lea(9), Aytug Kizilors(9), Shahram Kordasti(8), Robin Ireland(7), Ghulam Mufti(7), Ander Abarrategi(7), Thomas Seidl(6), Jie Jiang(5), Shreyans Gandhi(5), Benedetta Costantini(5), Linda Ariza‐McNaughton(5), Steven Best(5)