Karen McCoy

Nationwide Children's Hospital — United States

Medicine · Health Sciences

50h-index12.8kcitations241works1.02yr avg
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Research Topics

Cystic Fibrosis Research Advances(117), Neonatal Respiratory Health Research(49), Asthma and respiratory diseases(39), Inhalation and Respiratory Drug Delivery(30), Tracheal and airway disorders(29)

Publications238 total

101 Interim summary of SPL84-002, a Phase 2 study in pwCF carrying the 3849 +10 Kb C- >T mutation evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of SPL84
Journal of Cystic Fibrosis·2025
Intermittent Asthma and Risk of Severe Exacerbation in Children
CHEST Journal·2025· 1 citedOpen Access
A New Simple to Use Chest CT Scoring System: Validation Study
Pediatric Pulmonology·2025Open Access
Real -world impact of previous exposure to CFTR modulators on clinical parameters and chronic sinus disease in people with cystic fibrosis on elexacaftor-tezacaftor-ivacaftor
Respiratory Medicine·2025Open Access
CFTR mutation leads to intrinsic dysfunction in neutrophils from people with Cystic Fibrosis
2025· 1 citedOpen Access
1038 Prevalence of Restless Leg Syndrome in Children with Cystic Fibrosis
SLEEP·2025Open Access
Real-life impact of genotype and severity of lung disease on efficacy of elexacaftor-tezacaftor-ivacaftor in people with cystic fibrosis
Pulmonary Pharmacology & Therapeutics·2025· 3 citedOpen Access
Nocturnal Pediatric Asthma Exacerbations are Associated with Distinct Epithelial Circadian, Neuronal, and Inflammatory Networks
Journal of Allergy and Clinical Immunology·2025Open Access
Flow cytometric measurement of CFTR-mediated chloride transport in human neutrophils
Journal of Leukocyte Biology·2025· 2 cited
Mental Health of Pediatric Patients with Cystic Fibrosis after 18 Months on Elexacaftor‐Tezacaftor‐Ivacaftor Therapy
Pediatric Pulmonology·2024· 2 cited
Edinburgh postnatal depression scale score elevation in caregivers of infants with cystic fibrosis
Pediatric Pulmonology·2024· 1 citedOpen Access
Innate immune responses are increased in children with acute asthma exacerbation
Pediatric Allergy and Immunology·2024· 4 citedOpen Access
Author response for "Innate immune responses are increased in children with acute asthma exacerbation"
2024
Real-Life Impact of Genotype and Severity of Lung Disease on Efficacy of Elexacaftor-Tezacaftor-Ivacaftor in People with Cystic Fibrosis
SSRN Electronic Journal·2024Open Access
Increased innate immune responses in childen with acute asthma exacerbation
2023
Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy (ETI) for one-year and changes in chronic rhinosinusitis in people with cystic fibrosis (pwCF)
2023· 1 cited
Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy (ETI) for one-year and changes in structural lung disease in people with CF (pwCF)
2023
Elexacaftor-Tezacaftor-Ivacaftor Therapy for Chronic Sinus Disease in Cystic Fibrosis
JAMA Otolaryngology–Head & Neck Surgery·2023· 17 citedOpen Access
Impact of Elexacaftor–Tezacaftor–Ivacaftor on lung disease in cystic fibrosis
Pediatric Pulmonology·2023· 29 citedOpen Access
Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double‐blind, placebo‐controlled phase 1/2 clinical study
Journal of Cystic Fibrosis·2023· 119 citedOpen Access
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Frequent Co-authors

Bonnie W. Ramsey(12), Ronald L. Gibson(10), George Retsch‐Bogart(10), Margaret Rosenfeld(9), Robert G. Castile(8), Jennifer L. Taylor‐Cousar(7), Scott H. Donaldson(7), Ronald C. Rubenstein(7), Patrick A. Flume(6), Steven M. Rowe(6), Eva Van Braeckel(6), Manu Jain(6), Frank J. Accurso(6), Gregory S. Sawicki(6), Susanna A. McColley(5), Félix Ratjen(5), Sharon McNamara(5), Peter Hiatt(5), Carlos Milla(5), Benjamin T. Kopp(5)