Kathryn L. Pothoven

Northwestern University — United States

Immunology and Microbiology · Life Sciences

11h-index1.1kcitations22works0.02yr avg
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Research Topics

Immune Cell Function and Interaction(9), T-cell and B-cell Immunology(8), Asthma and respiratory diseases(6), Immunotherapy and Immune Responses(6), Diabetes and associated disorders(5)

Publications22 total

Retinoic acid promotes fibrinolysis and may regulate polyp formation
Journal of Allergy and Clinical Immunology·2022· 10 citedOpen Access
The barrier hypothesis and Oncostatin M: Restoration of epithelial barrier function as a novel therapeutic strategy for the treatment of type 2 inflammatory disease
Tissue Barriers·2017· 74 citedOpen Access
Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease
Journal of Allergy and Clinical Immunology·2016· 145 cited
Proton pump inhibitors decrease eotaxin-3/CCL26 expression in patients with chronic rhinosinusitis with nasal polyps: Possible role of the nongastric H,K-ATPase
Journal of Allergy and Clinical Immunology·2016· 74 citedOpen Access
Oncostatin M is produced by neutrophils, and promotes epithelial barrier dysfunction in mucosal airways disease
The Journal of Immunology·2016
Oncostatin M promotes epithelial barrier dysfunction and is elevated in eosinophilic mucosal disease (HYP7P.255)
The Journal of Immunology·2015· 1 cited
Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease
Journal of Allergy and Clinical Immunology·2015· 141 citedOpen Access
Oncostatin M Is Elevated in Mucosal Disease and May Mediate Epithelial Barrier Dysfunction in Vivo
Journal of Allergy and Clinical Immunology·2015
Oncostatin M Is Elevated In Chronic Rhinosinusitis and Decreases Barrier Function In Human Airway Epithelium
Journal of Allergy and Clinical Immunology·2014· 5 citedOpen Access
PLG Scaffold Delivered Antigen-Specific Regulatory T Cells Induce Systemic Tolerance in Autoimmune Diabetes
Tissue Engineering Part A·2013· 79 citedOpen Access
Ethylenecarbodiimide-Fixed Donor Splenocyte Infusions Differentially Target Direct and Indirect Pathways of Allorecognition for Induction of Transplant Tolerance
The Journal of Immunology·2012· 68 citedOpen Access
Donor-Specific CD8+Foxp3+ T Cells Protect Skin Allografts and Facilitate Induction of Conventional CD4+Foxp3+ Regulatory T Cells
American Journal of Transplantation·2012· 53 citedOpen Access
Rapamycin-Conditioned Donor Dendritic Cells Differentiate CD4+CD25+Foxp3+ T Cells In Vitro with TGF-β1 for Islet Transplantation
American Journal of Transplantation·2010· 33 citedOpen Access
RAPAMYCIN CONDITIONED DENDRITIC CELLS FOR IN VITRO DIFFERENTIATION OF DONOR-SPECIFIC CD4+CD25+FOXP3+ REGULATORY T CELLS FOR ISLET TRANSPLANTATION
Transplantation·2010
INDUCTION OF ALLOANTIGEN-SPECIFIC SUPPRESSIVE CD8+FOXP3+ T CELLS IN VITRO
Transplantation·2010Open Access
TOLEROGENIC ANTIGEN PRESENTING CELLS (APCS) ARE RESPONSIBLE FOR INDUCTION AND MAINTENANCE OF TOLERANCE TO ISLET ALLOGRAFTS BY ECDI-FIXED DONOR SPLENOCYTES.
Transplantation·2010
ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms
Proceedings of the National Academy of Sciences·2008· 163 citedOpen Access
DONOR CELL INFUSION WITHOUT IMMUNOSUPPRESSION AS A NOVEL THERAPY FOR INDUCTION OF DONOR-SPECIFIC TOLERANCE IN ISLET CELL TRANSPLANTATION
Transplantation·2008
Cutting Edge: TGF-β-Induced Expression of Foxp3 in T cells Is Mediated through Inactivation of ERK
The Journal of Immunology·2008· 72 citedOpen Access
Dendritic Cell–Dependent Induction of Beta Cell–Specific Regulatory T Cells for Suppression of Autoimmune Diabetes
Journal of Investigative Medicine·2007
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Frequent Co-authors

Xunrong Luo(10), Lydia Suh(8), David B. Conley(8), Robert C. Kern(8), Bruce K. Tan(8), Robert P. Schleimer(8), Stephanie S. Smith(7), Atsushi Kato(7), Leslie C. Grammer(7), Anju T. Peters(7), Josetta L. Houlihan(7), James E. Norton(6), Kathleen E. Harris(6), Kathryn E. Hulse(6), Taba Kheradmand(6), Roderick G. Carter(5), Kevin C. Welch(4), Mark C. Liu(4), Kristin V. Tarbell(3), Mathew DeGutes(3)