Zhen Shu

Emory University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index605citations20works9.52yr avg
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Research Topics

DNA Repair Mechanisms(3), Cancer-related molecular mechanisms research(3), Immunotherapy and Immune Responses(3), Galectins and Cancer Biology(3), MicroRNA in disease regulation(2)

Publications20 total

Abstract 4202: PD-L1 promotes DNA double-strand-break repair and radioresistance in cancer
Cancer Research·2025
PD-L1 deglycosylation promotes its nuclear translocation and accelerates DNA double-strand-break repair in cancer
Nature Communications·2024· 19 citedOpen Access
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
Nature Communications·2022· 25 citedOpen Access
Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition
Oncogene·2020· 25 cited
miR‐640 aggravates intervertebral disc degeneration via NF‐κB and WNT signalling pathway
Cell Proliferation·2019· 81 citedOpen Access
Downregulation of Protein Tyrosine Phosphatase Receptor Type R Accounts for the Progression of Hirschsprung Disease
Frontiers in Molecular Neuroscience·2019· 5 citedOpen Access
Nuclear galectin-1-FOXP3 interaction dampens the tumor-suppressive properties of FOXP3 in breast cancer
Cell Death and Disease·2018· 27 citedOpen Access
PRL-3 is a potential glioblastoma prognostic marker and promotes glioblastoma progression by enhancing MMP7 through the ERK and JNK pathways
Theranostics·2018· 38 citedOpen Access
The Diagnostic Performance of 68Ga-PET or PET/CT in Neuroendocrine Tumour, A Meta Analysis
Journal of Nuclear Medicine & Radiation Therapy·2018
A DPP-IV-resistant glucagon-like peptide-2 dimer with enhanced activity against radiation-induced intestinal injury
Journal of Controlled Release·2017· 11 cited
DDR2–CYR61–MMP1 Signaling Pathway Promotes Bone Erosion in Rheumatoid Arthritis Through Regulating Migration and Invasion of Fibroblast-Like Synoviocytes
Journal of Bone and Mineral Research·2016· 31 cited
A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis
Scientific Reports·2016· 145 citedOpen Access
Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro
Drug Design Development and Therapy·2015· 92 citedOpen Access
[Effects of irradiation on proliferation and differentiation of MC3T3-E1 osteoblastic cells in vitro].
PubMed·2014· 2 citedOpen Access
The Discoidin Domain Receptor 2/Annexin A2/Matrix Metalloproteinase 13 Loop Promotes Joint Destruction in Arthritis Through Promoting Migration and Invasion of Fibroblast‐like Synoviocytes
Arthritis & Rheumatology·2014· 29 citedOpen Access
Stromal Cell-Derived Factor-1 (SDF-1)/CXCR4 Axis Enhances Cellular Invasion in Ovarian Carcinoma Cells Via Integrin β1 and β3 Expressions
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics·2014· 12 citedOpen Access
Expression, purification and characterization of galectin-1 in Escherichia coli
Protein Expression and Purification·2014· 12 cited
Therapeutic Effects of PADRE-BAFF Autovaccine on Rat Adjuvant Arthritis
BioMed Research International·2014· 18 citedOpen Access
Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development
BMB Reports·2013· 17 citedOpen Access
TNFα induced FOXP3–NFκB interaction dampens the tumor suppressor role of FOXP3 in gastric cancer cells
Biochemical and Biophysical Research Communications·2012· 16 cited

Frequent Co-authors

Xiaochang Xue(12), Cun Zhang(9), Qiang Hao(9), Yingqi Zhang(9), Nan Mu(8), Weina Li(8), Wangqian Zhang(6), Tonglie Huang(5), Jintao Gu(4), Wei Zhang(4), Huadong Zhao(3), Meng Li(3), Xingming Deng(3), David S. Yu(3), Meng Li(2), Jin-Kang Zhao(2), Kuo Zhang(2), Wei Zhang(2), Nannan Liu(2), Kuo Zhang(2)