Anne J. Lenaerts

Colorado State University — United States

Medicine · Health Sciences

51h-index8.0kcitations134works1.32yr avg
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Research Topics

Tuberculosis Research and Epidemiology(93), Mycobacterium research and diagnosis(46), Cancer therapeutics and mechanisms(39), Pneumocystis jirovecii pneumonia detection and treatment(16), Infectious Diseases and Tuberculosis(14)

Publications134 total

Diaryl-Aminoindazole with Extensive In Vitro Mycobactericidal Activity Dependent on Exposure to Reactive Nitrogen Species
ACS Infectious Diseases·2026Open Access
The role of cytochrome bc1 inhibitors in future tuberculosis treatment regimens
Nature Communications·2025· 1 citedOpen Access
Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis
Antimicrobial Agents and Chemotherapy·2025Open Access
Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix- TB regimen in the relapsing BALB/c mouse model of tuberculosis
2025Open Access
Erratum for Peroutka-Bigus et al., “Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease”
Antimicrobial Agents and Chemotherapy·2025Open Access
Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease
Antimicrobial Agents and Chemotherapy·2025Open Access
Contribution of front-line, standard of care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease
2024· 1 citedOpen Access
Insights into the use of cytochrome bc1 inhibitors for future therapeutic strategies for tuberculosis
2024Open Access
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis
Antimicrobial Agents and Chemotherapy·2024· 5 citedOpen Access
Enhancing the therapeutic window for Spectinamide anti-tuberculosis Agents: Synthesis, Evaluation, and activation of phosphate prodrug 3408
Bioorganic & Medicinal Chemistry Letters·2024· 2 citedOpen Access
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis
2024· 1 citedOpen Access
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities
ACS Infectious Diseases·2024· 6 cited
Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model
Antimicrobial Agents and Chemotherapy·2023· 20 citedOpen Access
Drug Distribution and Efficacy of the DprE1 Inhibitor BTZ-043 in the C3HeB/FeJ Mouse Tuberculosis Model
Zenodo (CERN European Organization for Nuclear Research)·2023· 2 citedOpen Access
Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones
Antimicrobial Agents and Chemotherapy·2022· 24 citedOpen Access
Delamanid or pretomanid? A Solomonic judgement!
Journal of Antimicrobial Chemotherapy·2021· 60 citedOpen Access
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
Journal of Medicinal Chemistry·2021· 33 citedOpen Access
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis
ACS Infectious Diseases·2021· 27 citedOpen Access
Model-Based Meta-Analysis of Relapsing Mouse Model Studies from the Critical Path to Tuberculosis Drug Regimens Initiative Database
2021· 3 citedOpen Access
Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis
Antimicrobial Agents and Chemotherapy·2021· 24 citedOpen Access
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Frequent Co-authors

Veronica Gruppo(10), Richard Lee(9), Eric L. Nuermberger(8), Lisa K. Woolhiser(8), Michaël Scherman(7), Véronique Dartois(7), Ian M. Orme(7), Randall J. Basaraba(7), Martin I. Voskuil(7), Gavin J. Ryan(6), Scott M. Irwin(6), Scott G. Franzblau(6), Michael McNeil(5), Bernd Meibohm(5), Gregory T. Robertson(5), Mary Jackson(4), Emily Driver(4), Donald R. Hoff(4), Koen Andries(4), Helena I. Boshoff(4)