Eric C. Lai

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

84h-index31.9kcitations290works2.82yr avg
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Research Topics

MicroRNA in disease regulation(100), RNA Research and Splicing(99), RNA modifications and cancer(49), Developmental Biology and Gene Regulation(38), Chromosomal and Genetic Variations(37)

Publications290 total

Recurrent expansion and rapid evolution of the Drosophilid RNAi pathway in testis
2025Open Access
The use of natural stones for mitigating urban heat island intensity in LEED® perspective
Building and Environment·2025
Structure-informed evolutionary analysis of the meiotic recombination machinery
2025Open Access
Human DICER1 hotspot mutation induces both loss and gain of miRNA function
Nature Structural & Molecular Biology·2025· 4 cited
Human Dicer1 hotspot mutation induces both loss and gain of miRNA function
2025Open Access
Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance
2025Open Access
Repeated emergence of giant microRNA hairpins across invertebrates
Cell Reports·2025Open Access
518 Modeling of cancer mutations found in pediatric DICER1 syndrome informs novel therapeutic targeting strategies
Journal of Clinical and Translational Science·2025Open Access
Author Correction: Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision
Nature Methods·2025· 2 citedOpen Access
Double trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years
Nature Communications·2025· 9 citedOpen Access
The Use of Natural Stones for Mitigating Urban Heat Island Intensity in Leed® Perspective
SSRN Electronic Journal·2025Open Access
Noncanonical role of ALAS1 as a heme-independent inhibitor of small RNA–mediated silencing
Science·2024· 13 citedOpen Access
Mapping the microRNA landscape in the older adult brain and its genetic contribution to neuropsychiatric conditions
Nature Aging·2024· 8 citedOpen Access
The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs
Molecular Cell·2024· 15 citedOpen Access
PIWI-interacting RNAs: who, what, when, where, why, and how
The EMBO Journal·2024· 7 citedOpen Access
Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions
2024· 2 citedOpen Access
The structural landscape of Microprocessor mediated pri- <i>let-7</i> miRNA processing
2024· 2 citedOpen Access
Author response: The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition
2024Open Access
The rapidly evolving X-linked MIR-506 family fine-tunes spermatogenesis to enhance sperm competition
eLife·2024· 1 citedOpen Access
The Rapidly Evolving X-linked miR-506 Family Finetunes Spermatogenesis to Enhance Sperm Competition
2024Open Access
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Frequent Co-authors

Katsutomo Okamura(13), Jakub Orzechowski Westholm(7), Nicolas Robine(6), S Celniker(6), Eugène Berezikov(5), Thomas C. Kaufman(5), Brenton R. Graveley(5), Joseph W. Carlson(4), Michael O. Duff(4), Anastasia Samsonova(4), Norbert Perrimon(4), Peter Cherbas(4), Sol Shenker(4), David M. Tyler(4), Gerald M. Rubin(4), Wei‐Jen Chung(4), Raquel Martín-Folgar(4), Carrie Davis(3), Charles Yu(3), Elise A. Feingold(3)