Laurene Abjean

University of Geneva — Switzerland

Medicine · Health Sciences

6h-index537citations15works2.02yr avg
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Research Topics

Alzheimer's disease research and treatments(4), Genetic Neurodegenerative Diseases(4), RNA Research and Splicing(3), Neuroinflammation and Neurodegeneration Mechanisms(3), Tryptophan and brain disorders(2)

Publications15 total

Minute- and second-scale hippocampal network dysfunctions in the 3xTgAD mouse model of Alzheimer’s disease are prevented by TSPO knockout
2025Open Access
TSPO contributes to neuropathology and cognitive deficits in Alzheimer’s disease
Journal of Neuroinflammation·2025· 3 citedOpen Access
TSPO contributes to neuropathology and cognitive deficits in Alzheimer’s disease
2025Open Access
Non-linear microglial, inflammatory and oligodendrocyte dynamics across stages of Alzheimer's disease
Neurobiology of Disease·2025· 9 citedOpen Access
Non-linear microglial, inflammatory and oligodendrocyte dynamics across stages of Alzheimer’s disease
2025Open Access
Repeated low-intensity focused ultrasound led to microglial profile changes in TgF344-AD rats
2024Open Access
Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder
2023· 2 citedOpen Access
A seeding-based neuronal model of tau aggregation for use in drug discovery
PLoS ONE·2023· 8 citedOpen Access
Reactive astrocytes promote proteostasis in Huntington’s disease through the JAK2-STAT3 pathway
Brain·2022· 63 citedOpen Access
Reactive astrocytes promote proteostasis in Huntington’s disease through the JAK2-STAT3 pathway
2021· 8 citedOpen Access
P.106 Induction of aggregation by tau seeding in tauP301S-PS19 transgenic mice
European Neuropsychopharmacology·2020
Les astrocytes réactifs, des partenaires anti-agrégants dans la maladie de Huntington : identification des mécanismes impliqués dans le dialogue neurone-astrocyte
ZooKeys·2019Open Access
Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease
Acta Neuropathologica Communications·2018· 266 citedOpen Access
A42 Reactive astrocytes promote proteostasis in huntington’s disease
2018· 3 cited
The complex STATes of astrocyte reactivity: How are they controlled by the JAK–STAT3 pathway?
Neuroscience·2016· 175 citedOpen Access

Frequent Co-authors

Kelly Ceyzériat(9), Stergios Tsartsalis(7), Benjamin B. Tournier(7), Aurélien M. Badina(6), P. Millet(6), Lucile Ben Haim(5), María-Angeles Carrillo-de Sauvage(5), Carole Escartin(5), Quentin Amossé(5), Fanny Petit(4), Martine Guillermier(4), Alexis‐Pierre Bemelmans(4), Gilles Bonvento(4), Jean‐François Deleuze(4), Emmanuel Brouillet(4), Philippe Hantraye(4), Robert Olaso(4), Marie-Ange Palomares(3), Pauline Gipchtein(3), Marie‐Claude Gaillard(3)