Franca Fraternali

Institute of Structural and Molecular Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index6.4kcitations269works4.22yr avg
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Research Topics

Protein Structure and Dynamics(52), RNA and protein synthesis mechanisms(28), Monoclonal and Polyclonal Antibodies Research(25), Enzyme Structure and Function(19), Bioinformatics and Genomic Networks(18)

Publications269 total

Allosteric Ensembles Elucidate Mechanisms of Inhibition in Human Soluble Epoxide Hydrolase
2025Open Access
Leveraging protein language models and a scoring function for indel characterization and transfer learning
Patterns·2025Open Access
ImmunoMatch learns and predicts cognate pairing of heavy and light immunoglobulin chains
Nature Methods·2025Open Access
Refining the genetic landscape of anophthalmia and microphthalmia: a comprehensive framework with deep learning and updated gene panels
2025Open Access
Unravelling a new enzymatic activity of non-specific lipid transfer protein Cor a 8: A novel lipase from hazelnuts
International Journal of Biological Macromolecules·2025Open Access
Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspecies Apis mellifera mellifera
iScience·2025· 1 citedOpen Access
Tuning antibody stability and function by rational designs of framework mutations
mAbs·2025Open Access
Tumor-infiltrating CD27 <sup>-</sup> IgD <sup>-</sup> regulatory B cells suppress cytotoxic CD8 <sup>+</sup> T cell responses in renal cell carcinoma
2025Open Access
Redisulphid: A structural bioinformatic screen for identifying drug-targetable redox-regulated disulphides
Free Radical Biology and Medicine·2025
Multi-step antibody class switching in a primary human response is restricted after <i>IGHG2</i> and dependent on B cell maturation stage
2025Open Access
The need to implement FAIR principles in biomolecular simulations
Nature Methods·2025· 38 citedOpen Access
Assessing structure-function impacts on Vitellogenin by leveraging allelic variant occurring in honey bee subspecies <i>Apis mellifera meliffera</i>
2025Open Access
Tuning antibody stability and function by rational designs of framework mutations
2025Open Access
Leveraging protein language models and scoring function for Indel characterisation and transfer learning
2025· 1 citedOpen Access
ImmunoMatch learns and predicts cognate pairing of heavy and light immunoglobulin chains
2025· 3 citedOpen Access
AllohubPy: Detecting Allosteric Signals Through An Information-theoretic Approach
Journal of Molecular Biology·2025· 9 citedOpen Access
Assessing Structure-Function Impacts on Vitellogenin by Leveraging Allelic Variant Occurring in Honey Bee Subspecies Apis mellifera meliffera
SSRN Electronic Journal·2025· 1 citedOpen Access
Leveraging Protein Language Models and a Scoring Function for Indel Characterisation and Transfer Learning
SSRN Electronic Journal·2025· 1 citedOpen Access
TITINdb2—expanding annotation and structural information for protein variants in the giant sarcomeric protein titin
Bioinformatics Advances·2024· 2 citedOpen Access
TNIK: A redox sensor in endothelial cell permeability
Science Advances·2024· 5 citedOpen Access
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Frequent Co-authors

Flavia Autore(7), Jens Kleinjung(6), Joseph Ng(5), Deborah K. Dunn‐Walters(5), Paul R. Barber(4), Borivoj Vojnovic(4), Tony Ng(4), Annalisa Pastore(4), Gregory Weitsman(3), Toby J. Gibson(3), Christine Orengo(3), Giovanna Musco(3), Vincenzo Barone(3), Francesco Lelj(3), Roland G. Roberts(2), Christopher G. Mathew(2), Michael A. Simpson(2), Michael H. Malim(2), Alexander Stewart(2), Alfonso De Simone(2)