Thilo Köhler

University of Geneva — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index9.2kcitations147works1.32yr avg
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Research Topics

Antibiotic Resistance in Bacteria(53), Bacterial biofilms and quorum sensing(45), Antimicrobial Peptides and Activities(39), Bacterial Genetics and Biotechnology(30), Chemical Synthesis and Analysis(23)

Publications147 total

A microscale cultivation platform integrating OSMAC to explore metabolomic changes and antimicrobial activity of a fungal strain collection
Phytochemistry Letters·2025
Miniaturized high-throughput conversion of fungal strain collections into chemically characterized extract libraries for antimicrobial discovery
Frontiers in Chemistry·2025Open Access
Phenylalkyl Acetophenones and Anacardic Acids from Knema oblongifolia with Synthetic Analogues as Anti-infectives and Antibacterial Agents
ACS Bio & Med Chem Au·2025Open Access
Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space
Angewandte Chemie·2025Open Access
Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space
Angewandte Chemie International Edition·2025· 3 citedOpen Access
Multidrug efflux pumps of Pseudomonas aeruginosa show selectivity for their natural substrates
Frontiers in Microbiology·2025· 2 citedOpen Access
Stereorandomized Oncocins with Preserved Ribosome Binding and Antibacterial Activity
Journal of Medicinal Chemistry·2024· 4 citedOpen Access
Antimicrobial Peptide–Peptoid Hybrids with and without Membrane Disruption
ACS Infectious Diseases·2023· 19 citedOpen Access
Short Lecture "A high-throughput and cost-effective metabolomic based platform to overcome natural products screening limitations for antimicrobial drug discovery"
Planta Medica·2023
Generation of potent antibacterial compounds through enzymatic and chemical modifications of the trans-δ-viniferin scaffold
Scientific Reports·2023· 11 citedOpen Access
Author Correction: Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
Nature Communications·2023· 4 citedOpen Access
Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
Nature Communications·2023· 74 citedOpen Access
Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
2023Open Access
Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
2023Open Access
Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
To fold or not to fold: diastereomeric optimization of an α-helical antimicrobial peptide
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide
Journal of Medicinal Chemistry·2023· 24 citedOpen Access
To fold or not to fold: diastereomeric optimization of an α-helical antimicrobial peptide
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium
JCI Insight·2023· 11 citedOpen Access
An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening
Cell Reports Physical Science·2022· 19 citedOpen Access
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Frequent Co-authors

Christian van Delden(23), Patrick Plésiat(6), Lasta Kocjancic Curty(5), Jean‐Louis Reymond(5), Alexandre Lüscher(5), Jean-Claude Péchère(4), Jean-Claude Péchère(4), J C Pechère(4), Christian van Delden(3), Simone F. Epp(3), M M Hamzehpour(3), Angus Buckling(3), M. Michéa-Hamzehpour(3), Thissa N. Siriwardena(3), Bee‐Ha Gan(3), Sacha Javor(3), Tamis Darbre(3), Daniel Pletzer(3), Malcolm G. P. Page(3), Rachel Comte(2)