Michael A. Caligiuri

City Of Hope National Medical Center — United States

Immunology and Microbiology · Life Sciences

135h-index69.5kcitations864works6.82yr avg
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Research Topics

Immune Cell Function and Interaction(338), Acute Myeloid Leukemia Research(155), Virus-based gene therapy research(121), T-cell and B-cell Immunology(102), CAR-T cell therapy research(99)

Publications862 total

Comparative efficacy and safety of PSCA CAR-engineered Vδ1 γδ T cells for immunotherapy of pancreatic cancer
Journal for ImmunoTherapy of Cancer·2025· 2 citedOpen Access
Loss of YTHDF2 enhances Th9 programming and CAR-Th9 cell antitumor efficacy
Nature Immunology·2025· 4 cited
CAR-T cells targeting CD155 reduce tumor burden in preclinical models of leukemia and solid tumors
Journal of Clinical Investigation·2025· 3 citedOpen Access
YTHDF2: a key RNA reader and antitumor target
Trends in Immunology·2025· 17 citedOpen Access
Natural killer cell–based immunotherapy for cancer
The Journal of Immunology·2025· 14 citedOpen Access
Off-the-shelf invariant NKT cells expressing anti-PSCA CAR and IL-15 promote pancreatic cancer regression in mice
Journal of Clinical Investigation·2025· 5 citedOpen Access
Interim report on engineered NK cell trial in lung cancer refractory to immune checkpoint inhibitors
JCI Insight·2025· 7 citedOpen Access
miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape
Nature Communications·2025· 2 citedOpen Access
NKp46 enhances type 1 innate lymphoid cell proliferation and function and anti-acute myeloid leukemia activity
Nature Communications·2025· 4 citedOpen Access
A First-in-Human Dose Escalation Clinical Trial of Engineered Natural Killer Cell Therapy in Non-Small Cell Lung Cancer Patients Refractory to Immune Check Point Inhibitors
Blood·2024
924 Disruption of m6A reader protein YTHDF2 enhances Th9 cell differentiation and potentiates the anti-tumor efficacy of CAR Th9 cells
Regular and Young Investigator Award Abstracts·2024Open Access
Epigenetic Activation of the EBV Protein Kinase Determines Antiviral Drug Response in Central Nervous System Lymphoma
2024Open Access
Isolation, expansion, and adoptive transfer of human ILC2s for the treatment of mice bearing liquid and solid tumors
STAR Protocols·2024· 1 citedOpen Access
Enhanced treatment of breast cancer brain metastases with oncolytic virus expressing anti-CD47 antibody and temozolomide
Molecular Therapy Oncology·2024· 4 citedOpen Access
Supplementary Table S1 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
Supplementary Figure S6 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
Supplementary Table S1 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
Supplementary Figure S2 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
Supplementary Figure S4 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
Supplementary Figure S3 from Preclinical Evaluation of Off-The-Shelf PD-L1<sup>+</sup> Human Natural Killer Cells Secreting IL15 to Treat Non–Small Cell Lung Cancer
2024Open Access
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Frequent Co-authors

Todd A. Fehniger(11), Clara D. Bloomfield(10), Jianhua Yu(8), Guido Marcucci(8), Megan A. Cooper(7), Susan P. Whitman(6), Bayard L. Powell(6), Jonathan E. Kolitz(6), Richard A. Larson(6), Aharon G. Freud(6), Danilo Perrotti(5), Kati Maharry(5), Michael D. Radmacher(5), Krzysztof Mrózek(5), Andrew J. Carroll(5), Ramasamy Santhanam(4), Carlo M. Croce(4), Brian Becknell(4), Hsiaoyin Mao(4), Heiko Becker(4)