L. van der Wee-Pals

Leiden University Medical Center — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index1.8kcitations15works0.02yr avg
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Research Topics

Bone Metabolism and Diseases(8), Bone health and treatments(5), Bone health and osteoporosis research(3), Radiopharmaceutical Chemistry and Applications(2), MicroRNA in disease regulation(1)

Publications15 total

Dietary Mannan Oligosaccharides Modulate Gut Microbiota, Increase Fecal Bile Acid Excretion, and Decrease Plasma Cholesterol and Atherosclerosis Development
Molecular Nutrition & Food Research·2018· 90 citedOpen Access
Effect of MSC treatment on LPS-induced inflammation, emphysema and atherosclerosis in<i>E3L</i>mice
2015
Sclerostin in Mineralized Matrices and van Buchem Disease
Journal of Dental Research·2009· 137 cited
Genetically Engineered KSFrt Mesenchymal Progenitors Cells in Combination with Whole Body Optical Imaging Provide an Excellent Model to Study Effects on Cell Fate, Bone and Cartilage Formation and Biomaterials
Data Archiving and Networked Services (DANS)·2008
<i>SOST</i> expression is restricted to the great arteries during embryonic and neonatal cardiovascular development
Developmental Dynamics·2006· 44 citedOpen Access
Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist
The Journal of Experimental Medicine·2004· 876 citedOpen Access
Dissociation of Angiogenesis and Osteoclastogenesis During Endochondral Bone Formation in Neonatal Mice
Journal of Bone and Mineral Research·2002· 85 cited
Ovariectomy and orchidectomy induce a transient increase in the osteoclastogenic potential of bone marrow cells in the mouse
Bone·1997· 49 cited
Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro.
Journal of Clinical Investigation·1996· 306 citedOpen Access
In vitro and Ex vivo evidence that estrogens suppress increased bone resorption induced by ovariectomy or PTH stimulation through an effect on osteoclastogenesis
Journal of Bone and Mineral Research·1995· 46 cited
Effects of experimental conditions on the release of 45calcium from prelabeled fetal mouse long bones
Bone·1995· 27 cited
Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: Application to the study of intravenous 14C-labeled 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate
Journal of Bone and Mineral Research·1994· 2 cited
Leukemia inhibitory factor inhibits osteoclastic resorption, growth, mineralization, and alkaline phosphatase activity in fetal mouse metacarpal bones in culture
Journal of Bone and Mineral Research·1993· 59 cited
Two Distinct Effects of Recombinant Human Tumor Necrosis Factor-a on Osteoclast Development and Subsequent Resorption of Mineralized Matrix*
Endocrinology·1991· 91 cited
Sclerostin expression is absent in cementocytes in teeth and in osteocytes in bone biopsies of patients with van Buchem disease
Data Archiving and Networked Services (DANS)· 3 cited

Frequent Co-authors

Socrates E. Papapoulos(11), Clemens W.G.M. Löwik(11), Gabri van der Pluijm(3), W. Most(3), Rutger L. van Bezooijen(2), Annemieke Visser(2), Marcel Karperien(2), Herman A. Hamersma(2), Peter ten Dijke(2), E. van Beek(2), R.L. van Bezooijen(2), A.L.J.J. Bronckers(2), Richmond A. Th. Gortzak(2), Pancras C.W. Hogendoorn(2), Wendy Balemans(2), Frederik G. Dikkers(2), A. Ederveen(2), Bernard A.J. Roelen(1), Edwin de Wilt(1), H J Vloedgraven(1)