Yingchao Hu

Nanjing Medical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index674citations27works6.82yr avg
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Research Topics

Inflammasome and immune disorders(9), Neuroinflammation and Neurodegeneration Mechanisms(4), Hippo pathway signaling and YAP/TAZ(4), Immune Cell Function and Interaction(3), T-cell and B-cell Immunology(2)

Publications27 total

DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity
Cell Reports·2025· 2 citedOpen Access
Identification of two repurposed drugs targeting GSDMD oligomerization interface I to block pyroptosis
Cell chemical biology·2024· 19 cited
Experimental verification about treatment of Bu-Shen-Yi-Jing-Fang in Alzheimer’s disease by the analysis of the feasible signaling pathway of network pharmacology
BMC Complementary Medicine and Therapies·2024· 2 citedOpen Access
ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis
Nature Cell Biology·2024· 12 cited
GSDMD protects intestinal epithelial cells against bacterial infections through its N-terminal activity affecting intestinal immune homeostasis
Journal of Biomedical Research·2024· 2 citedOpen Access
Catalpol alleviates amyloid- generation and neuronal oxidative stress injury via activating the Keap1-Nrf2/ARE signaling pathway in the immortalized lymphocytes from patients with late-onset Alzheimer's disease and SKNMC cells co-culture model.
PubMed·2024· 4 citedOpen Access
ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP Protein
Advanced Science·2023· 10 citedOpen Access
The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11
Proceedings of the National Academy of Sciences·2022· 42 citedOpen Access
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
Cell Reports·2022· 46 citedOpen Access
Microglial <scp>AIM2</scp> alleviates antiviral‐related neuro‐inflammation in mouse models of Parkinson's disease
Glia·2022· 25 cited
ECSIT is a critical factor for controlling intestinal homeostasis and tumorigenesis through regulating the translation of YAP protein
Research Square (Research Square)·2022Open Access
ECSIT is a critical factor for controlling intestinal homeostasis and tumorigenesis through regulating the translation of YAP protein
Research Square (Research Square)·2022· 1 citedOpen Access
Key role for mitochondrial complex I assembly factor ECSIT and mitochondrial metabolism in controlling intestinal homeostasis and tumorigenesis by regulation of translation of YAP protein
2022Open Access
Gasdermin D Restricts Anti-Tumor Immunity During PD-L1 Checkpoint Blockade
SSRN Electronic Journal·2022· 2 citedOpen Access
Pyroptosis, and its Role in Central Nervous System Disease
Journal of Molecular Biology·2021· 107 cited
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro
Chemico-Biological Interactions·2021· 31 cited
RNF31 mediated ubiquitination of A20 aggravates inflammation and hepatocyte apoptosis through the TLR4/MyD88/NF-κB signaling pathway
Chemico-Biological Interactions·2021· 15 cited
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis
The Journal of Experimental Medicine·2021· 93 citedOpen Access
&lt;p&gt;Phosphoproteomics Reveals Key Regulatory Kinases and Modulated Pathways Associated with Ovarian Cancer Tumors&lt;/p&gt;
OncoTargets and Therapy·2020· 8 citedOpen Access
Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation
Molecular Cell·2020· 84 citedOpen Access
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Frequent Co-authors

Bingwei Wang(15), Shuo Yang(14), Chunmei Ma(11), Yuying Jiang(9), Sheng Li(8), Yongbing Yang(8), Paul N. Moynagh(7), Shuang Wen(7), Yuqing Wu(5), Chanyuan Ma(4), Chunyan Wu(4), Lu Liu(4), Xue Liu(3), Jiawei Zhou(3), Fiachra Humphries(3), Xi Wang(3), Yunwei Lu(3), Renjuan Hao(3), Guran Yu(3), Chunyan Wu(2)