Shivam A. Zaver

University of Pennsylvania — United States

Immunology and Microbiology · Life Sciences

11h-index1.1kcitations31works10.02yr avg
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Research Topics

interferon and immune responses(18), Viral Infections and Vectors(7), Immune Response and Inflammation(5), Genetic and rare skin diseases.(5), RNA regulation and disease(5)

Publications31 total

Sequence Diversity in the 3′ Untranslated Region of Alphavirus Modulates IFIT2-Dependent Restriction in a Cell Type-Dependent Manner
Journal of Interferon & Cytokine Research·2025· 2 citedOpen Access
ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
Cell·2025· 14 cited
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology
JCI Insight·2024· 4 citedOpen Access
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology
2024· 1 citedOpen Access
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P
Science Signaling·2024· 29 citedOpen Access
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease
JCI Insight·2023· 25 citedOpen Access
The proto-oncogene SRC phosphorylates cGAS to inhibit an antitumor immune response
JCI Insight·2023· 13 citedOpen Access
ISID0321 - A human tissue model of Darier disease reveals MEK as a novel therapeutic target downstream of SERCA2 deficiency
2023
Targeting SERCA2 in organotypic epidermis reveals MEK inhibition as a therapeutic strategy for Darier disease
2023· 3 citedOpen Access
Live Imaging with Genetically Encoded Physiologic Sensors and Optogenetic Tools
Journal of Investigative Dermatology·2023· 8 citedOpen Access
STING activation depends on ACBD3 and other phosphatidylinositol 4-phosphate-regulating proteins
2022Open Access
The proto-oncogene c-Src phosphorylates cGAS to reduce DNA binding and activation
2022Open Access
Sequence diversity in the 3’ untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent manner
2021· 5 citedOpen Access
Endomembrane targeting of human OAS1 p46 augments antiviral activity
eLife·2021· 76 citedOpen Access
A Rationally Designed c-di-AMP Förster Resonance Energy Transfer Biosensor To Monitor Nucleotide Dynamics
Journal of Bacteriology·2021· 4 citedOpen Access
Author response: Endomembrane targeting of human OAS1 p46 augments antiviral activity
2021· 1 citedOpen Access
4-Hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen
eLife·2021· 13 citedOpen Access
Endomembrane targeting of human OAS1 p46 augments antiviral activity
2021· 8 citedOpen Access
Author response: 4-Hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen
2021Open Access
A rationally designed c-di-AMP FRET biosensor to monitor nucleotide dynamics
2021Open Access
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Frequent Co-authors

Joshua J. Woodward(19), Alex J. Pollock(6), Rutger D. Luteijn(5), Liberty Onia(5), David H. Raulet(5), Johannes Schwerk(5), Jennifer Hyde(5), Cory L. Simpson(5), Genhong Cheng(4), Afua Tiwaa(4), Jóhann E. Guðjónsson(4), Michelle S. Parvatiyar(3), Benjamin G. Gowen(3), Stacia K. Wyman(3), Nick E. Garelis(3), Sarah M. McWhirter(3), George E. Katibah(3), Jacob E. Corn(3), Frank Soveg(3), Nandan S. Gokhale(3)