Gabriel F. Alencar

Carter Center — United States

Immunology and Microbiology · Life Sciences

16h-index3.5kcitations40works6.32yr avg
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Research Topics

Atherosclerosis and Cardiovascular Diseases(11), Forensic and Genetic Research(6), Single-cell and spatial transcriptomics(6), Race, Genetics, and Society(6), Adipokines, Inflammation, and Metabolic Diseases(5)

Publications40 total

339 Engineered T cell therapy combined with PD-1, Lag-3 and Tim-3 checkpoint inhibition promotes pro-inflammatory CD4 T cell differentiation in an ovarian cancer mouse model
Regular and Young Investigator Award Abstracts·2025Open Access
Triple checkpoint blockade, but not anti-PD-1 alone, enhances engineered adoptive T cell therapy in a mouse model of advanced ovarian cancer 2090
The Journal of Immunology·2025Open Access
Glucocorticoids Disrupt Smooth Muscle Cell-Mediated Plaque Stabilization via Glucocorticoid Receptor-Dependent Inhibition of PDGF/TGFB Signaling
Free Radical Biology and Medicine·2025
Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
B cell responses specific for polyomavirus-derived oncoprotein are predictive of Merkel cell carcinoma tumor control
2025Open Access
Merkel cell carcinoma-derived macrophage migration inhibitory factor (MIF) may promote persistence of Chronic Lymphocytic Leukemia
2024Open Access
Novel Mouse Model of Myocardial Infarction, Plaque Rupture, and Stroke Shows Improved Survival With Myeloperoxidase Inhibition
Circulation·2024· 39 citedOpen Access
IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice
Arteriosclerosis Thrombosis and Vascular Biology·2024· 10 citedOpen Access
Obesogenic diet disrupts tissue-specific mitochondrial gene signatures in the artery and capillary endothelium
Physiological Genomics·2023· 7 citedOpen Access
IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering
2023Open Access
Mouse Model of Heart Attack and Stroke Shows Improved Survival with MPO Inhibition
2023Open Access
Loss of endothelial cell heterogeneity in arteries after obesogenic diet
2023Open Access
Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets
Atherosclerosis·2021· 56 citedOpen Access
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms
Nature Metabolism·2021· 159 citedOpen Access
Novel Therapeutic Manipulations of Smooth Muscle Cell Metabolism to Enhance Atherosclerotic Fibrous Cap Stability
Free Radical Biology and Medicine·2020
KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation
Arteriosclerosis Thrombosis and Vascular Biology·2020· 33 citedOpen Access
Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells
Circulation Research·2020· 99 citedOpen Access
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis
Circulation·2020· 367 citedOpen Access
Revealing the Origins of Foam Cells in Atherosclerotic Lesions
Arteriosclerosis Thrombosis and Vascular Biology·2019· 55 citedOpen Access
Abstract 17184: Nearly One Third of GWAS CAD Are Putative SMC Klf4 or Oct4 Targets in Advanced Atherosclerotic Lesions
Circulation·2018
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Frequent Co-authors

Gary K. Owens(20), Silviene Fabiana de Oliveira(10), Laura S. Shankman(9), Stefan Bekiranov(9), Carolina Carvalho Gontijo(9), Rebecca A. Deaton(8), N.M.O. Godinho(8), Santosh Karnewar(7), Carlos Eduardo G. Amorim(7), Ryan M. Haskins(6), Brant E. Isakson(6), Katherine Owsiany(6), Richard A. Baylis(6), Maria Angélica F. Pedrosa(6), Marcelo R. Luizon(6), Aguinaldo Luíz Simões(6), Delphine Gomez(5), Alexandra Newman(5), Sohel Shamsuzzaman(5), Vlad Serbulea(5)