Manish J. Butte

University of California, Los Angeles — United States

Immunology and Microbiology · Life Sciences

62h-index28.8kcitations303works4.72yr avg
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Research Topics

Immunodeficiency and Autoimmune Disorders(74), Genomics and Rare Diseases(34), Immune Cell Function and Interaction(32), T-cell and B-cell Immunology(28), Cellular Mechanics and Interactions(19)

Publications280 total

Clinical and Genetic Insights into Partial RAG Deficiency in Adults: When to Consider Hematopoietic Stem Cell Transplantation?
Journal of Human Immunity·2025Open Access
Systematic functional validation of IKAROS variants from patients and laboratory-generated mutations
Blood Advances·2025Open Access
Type-2 immune skewing in patients with disseminated coccidioidomycosis
2025Open Access
Proceedings of the second Artificial Intelligence in Primary Immunodeficiency (AIPI) meeting
Journal of Allergy and Clinical Immunology·2025· 1 cited
The Use of Genetics and Immunology in the Diagnosis and Care of Advanced Coccidioidomycosis: Where Are We Going?
Journal of Fungi·2025· 1 citedOpen Access
Current perspectives and challenges of using artificial intelligence in immunodeficiencies
Journal of Allergy and Clinical Immunology·2025· 6 citedOpen Access
Hyaluronan Accumulates in Inflamed Lymph Nodes and Promotes B‐Cell Activation
Proteoglycan Research·2025· 1 citedOpen Access
Factors associated with and kinetics of anti–IFN-α autoantibodies in RAG1/2 deficiency
Journal of Allergy and Clinical Immunology Global·2025Open Access
Pluripotent stem cell–derived extracellular vesicles for systemic immune modulation in diabetes therapy
2025· 1 citedOpen Access
Latent Profile Analyses of Circulatory Biomarkers Indicate Distinct Patterns of Inflammation in Response to Transfusion in Pediatric MODS
American Journal of Respiratory and Critical Care Medicine·2025
Differential Correlation Network Analysis Illustrates Novel Biomarker Interactions Underlying Hyperinflammation in Pediatric ARDS
American Journal of Respiratory and Critical Care Medicine·2025
Elapegademase in Patients with ADA-SCID Previously Treated with Pegademase: A Case Series
Journal of Human Immunity·2025Open Access
Clinical Scoring of Immune Deficiency and Dysregulation Correlated with Immune Biomarkers in Mennonite Patients with Hypomorphic RAG1 Variant Clinical Scoring of Immune Deficiency in Hypomorphic RAG
Journal of Human Immunity·2025Open Access
Functional Characterization of a Hypomorphic IL-17A Variant Associated with Recurrent Pneumonias
Journal of Human Immunity·2025Open Access
Primary and Safety Outcomes of a Phase 3 Open-Label, Single-Arm, 12-Week Study of Treatment with PI3Kδ Inhibitor Leniolisib in Pediatric Patients Aged 4–11 Years with Activated PI3Kδ Syndrome (APDS)
Journal of Human Immunity·2025Open Access
Immunomodulation in the Treatment of Disseminated Coccidioidomycosis
Journal of Human Immunity·2025· 2 citedOpen Access
Gut dysbiosis patterns in CVID patients with noninfectious complications observed in a germ-free mouse model through fecal microbiota transplantation
Journal of Human Immunity·2025Open Access
Multi-Year Registry Study of Elapegademase Treatment in Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) Requiring Enzyme Replacement Therapy
Journal of Clinical Immunology·2025· 1 citedOpen Access
Piloting an automated query and scoring system to facilitate APDS patient identification from health systems
Frontiers in Immunology·2025· 4 citedOpen Access
Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature
Science Immunology·2025· 9 citedOpen Access
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Frequent Co-authors

Luigi D. Notarangelo(8), Megan A. Cooper(7), Gordon J. Freeman(5), Arlene H. Sharpe(5), George M. Whitesides(5), Catherine M. Biggs(5), Petter Brodin(5), Giorgio Casari(5), Antônio Condino‐Neto(5), Jacques Fellay(5), José Luis Franco(5), David Hagin(5), Joshua D. Milner(5), Trine H. Mogensen(5), Carolina Prando(5), Karin Chen(5), Paul L. Bollyky(4), Kenneth H. Hu(4), Laurent Abel(4), Alessandro Aiuti(4)