Christopher S. McGinnis

Palo Alto University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index6.5kcitations50works20.62yr avg
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Research Topics

Single-cell and spatial transcriptomics(29), Cancer Genomics and Diagnostics(11), Cancer Cells and Metastasis(8), Immune cells in cancer(8), Genomics and Chromatin Dynamics(4)

Publications49 total

FAK Inhibition Remodels the Metastatic ECM and Restores CD8⁺ T Cell Trafficking and Immunosurveillance
2026
Erythropoietin receptor on cDC1s dictates immune tolerance
Nature·2025· 1 citedOpen Access
T cell engagers control solid tumors through clonal replacement and IL2-driven effector differentiation of CD8 T cells
2025Open Access
Cell cycle-coupled transcriptional network orchestrates human B cell fate bifurcation
2025· 1 citedOpen Access
Translation dysregulation in cancer as a source for targetable antigens
Cancer Cell·2025· 14 citedOpen Access
Reducing batch effects in single cell chromatin accessibility measurements by pooled transposition with MULTI-ATAC
2025· 2 citedOpen Access
Mapping enhancer-gene regulatory interactions from single-cell data
2024· 15 citedOpen Access
Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes
Journal of Clinical Investigation·2024· 17 citedOpen Access
MULTI-seq sample multiplexing for 10x Genomics RNA+ATAC multiomic profiling v1
2024Open Access
The temporal progression of lung immune remodeling during breast cancer metastasis
Cancer Cell·2024· 47 citedOpen Access
Patterning and folding of intestinal villi by active mesenchymal dewetting
Cell·2024· 65 citedOpen Access
Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
Nature Cell Biology·2024· 60 citedOpen Access
Referee report. For: Tumor-driven stromal reprogramming in the pre-metastatic lymph node [version 1; peer review: 2 approved with reservations]
Faculty of 1000 Research Ltd·2024Open Access
Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
2023· 9 citedOpen Access
Patterning and folding of intestinal villi by active mesenchymal dewetting
2023· 8 citedOpen Access
Single-cell RNA sequencing of 76,535 capillary PBMCs from 3 donors across 28 samples, freshly isolated or on ice for 24h with manual 4-layer annotation hierarchy
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Single-cell RNA sequencing of 76,535 capillary PBMCs from 3 donors across 28 samples, freshly isolated or on ice for 24h with manual 4-layer annotation hierarchy
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
The temporal progression of immune remodeling during metastasis
2023· 5 citedOpen Access
D-SPIN constructs gene regulatory network models from multiplexed scRNA-seq data revealing organizing principles of cellular perturbation response
2023· 20 citedOpen Access
The Temporal Progression of Immune Remodeling During Metastasis
SSRN Electronic Journal·2023Open Access
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Frequent Co-authors

Zev J. Gartner(34), Eric D. Chow(13), David M. Patterson(10), Jonathan S. Weissman(8), Ansuman T. Satpathy(8), Juliane Winkler(7), Lyndsay M. Murrow(6), William M. Rideout(6), Kyung Hoi Min(6), Raymond Ho(6), Wei Wu(6), Joseph M. Replogle(6), Jennifer L. Page(6), Felix Horns(6), Xiaojie Qiu(6), Michael Z. Chen(6), William A. Freed-Pastor(6), Trever G. Bivona(6), Michelle M. Chan(6), Nir Yosef(6)