D. Gatehouse

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.3kcitations72works0.02yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(37), Effects and risks of endocrine disrupting chemicals(9), DNA and Nucleic Acid Chemistry(7), DNA Repair Mechanisms(5), Drug Transport and Resistance Mechanisms(5)

Publications72 total

“Aspartame: A review of genotoxicity data”
Food and Chemical Toxicology·2015· 47 citedOpen Access
Bacterial Mutagenicity Assays: Test Methods
Methods in molecular biology·2011· 57 cited
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2011· 229 cited
<i>In Vitro</i> Genotox Assays
2010· 2 cited
An evaluation of the genotoxicity of the antitussive drug Dextromethorphan
Regulatory Toxicology and Pharmacology·2007· 5 cited
Short‐Term Testing for Genotoxicity
The Cancer Handbook·2007
The pathogen reduction treatment of platelets with S-59 HCl (Amotosalen) plus ultraviolet A light: Genotoxicity profile and hazard assessment
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2007· 26 cited
In vivo erythrocyte micronucleus assay
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2006· 114 cited
Short‐Term Testing for Genotoxicity
The Cancer Handbook·2005
Characterization of DNA Damage at Purine Residues in Oligonucleotides and Calf Thymus DNA Induced by the Mutagen 1-Nitrosoindole-3-acetonitrile
Chemical Research in Toxicology·2001· 18 citedOpen Access
Flow cytometric enumeration of micronucleated reticulocytes: High transferability among 14 laboratories
Environmental and Molecular Mutagenesis·2001· 51 cited
In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring
Environmental and Molecular Mutagenesis·2000· 21 cited
In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring
Environmental and Molecular Mutagenesis·2000· 241 cited
Efficient Nitroso Group Transfer fromN-Nitrosoindoles to Nucleotides and 2′-Deoxyguanosine at Physiological pH
Journal of Biological Chemistry·1999· 60 citedOpen Access
P I.13 The genotoxicity profile of a new Trinem antibiotic, sanfetrinem cilexetil
Mutation research. Fundamental and molecular mechanisms of mutagenesis·1997
Removal of a retained T-tube from the common bile duct.
PubMed·1997· 6 cited
Recommendations for the performance of bacterial mutation assays
Mutation Research/Environmental Mutagenesis and Related Subjects·1994· 224 cited
Report of the BTS/UKEMS Working Group on Dose Setting in In-Vivo Mutagenicity Assays
Human & Experimental Toxicology·1993· 4 cited
Collaborative study to evaluate the inter/intra laboratory reproducibility and phenotypic stability of Salmonella typhimurium TA97a and TA102
Mutagenesis·1993· 11 cited
Mutation, cancer and transgenic models: relevance to the toxicology industry
Mutagenesis·1993· 21 cited
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Frequent Co-authors

David Tweats(9), M R B Keighley(6), D.J. Wedd(5), S. Pascoe(5), Stephen D. Dertinger(4), David Kirkland(4), Philip E. Wilcox(4), Brian Burlinson(4), Geoffrey Stemp(4), James T. MacGregor(3), David H. Blakey(3), G. Krishna(3), Takeshi Morita(3), Antonella Russo(3), J Alexander-Williams(3), Y Arabi(3), Carl Westmoreland(3), Makoto Hayashi(2), I.‐D. Adler(2), Shizuyo Sutou(2)