Anthony W. Siadak

Seattle University — United States

Medicine · Health Sciences

20h-index2.9kcitations29works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(13), T-cell and B-cell Immunology(8), Glycosylation and Glycoproteins Research(5), Cell Adhesion Molecules Research(5), Immune Cell Function and Interaction(5)

Publications29 total

Glycovariant anti-CD37 monospecific protein therapeutic exhibits enhanced effector cell-mediated cytotoxicity against chronic and acute B cell malignancies
mAbs·2013· 12 citedOpen Access
GlycoVariant Anti-CD37 Small Modular Immuno-Pharmaceutical Exhibits Superior Natural Killer Cell Mediated Cytotoxicity Against Chronic Lymphocytic Leukemia Cells at Low Concentrations and Low Antigen Density
Blood·2010· 1 cited
<i>In vivo</i>Drug-Linker Stability of an Anti-CD30 Dipeptide-Linked Auristatin Immunoconjugate
Clinical Cancer Research·2005· 278 citedOpen Access
Functional Analysis of the Matricellular Protein SPARC with Novel Monoclonal Antibodies
Journal of Histochemistry & Cytochemistry·2004· 45 citedOpen Access
Expression and Characterization of Murine Hevin (SC1), a Member of the SPARC Family of Matricellular Proteins
Journal of Histochemistry & Cytochemistry·2004· 59 citedOpen Access
Anti-CD40 therapy extends renal allograft survival in rhesus macaques1
Transplantation·2002· 159 cited
Thrombospondin 2 Inhibits Microvascular Endothelial Cell Proliferation by a Caspase-independent Mechanism
Molecular Biology of the Cell·2002· 108 citedOpen Access
Differential Regulation of CD40-Mediated Human B Cell Responses by Antibodies Directed against Different CD40 Epitopes
Cellular Immunology·2000· 15 cited
4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses
The Journal of Experimental Medicine·1997· 787 citedOpen Access
Characterization of mouse ALCAM (CD166): the CD6‐binding domain is conserved in different homologs and mediates cross‐species binding
European Journal of Immunology·1997· 81 citedOpen Access
Identification of Residues in CD6 Which Are Critical for Ligand Binding
Biochemistry·1997· 39 cited
Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.
PubMed·1997· 5 cited
The Amino-terminal Immunoglobulin-like Domain of Activated Leukocyte Cell Adhesion Molecule Binds Specifically to the Membrane-proximal Scavenger Receptor Cysteine-rich Domain of CD6 with a 1:1 Stoichiometry
Journal of Biological Chemistry·1996· 95 citedOpen Access
Characterization of mouse CD6 with novel monoclonal antibodies which enhance the allogeneic mixed leukocyte reaction
European Journal of Immunology·1996· 30 cited
Analysis of gp39/CD40 Interactions Using Molecular Models and Site-Directed Mutagenesis
Biochemistry·1995· 59 cited
The Membrane-proximal Scavenger Receptor Cysteine-rich Domain of CD6 Contains the Activated Leukocyte Cell Adhesion Molecule Binding Site
Journal of Biological Chemistry·1995· 92 citedOpen Access
Identification of Residues on CD40 and Its Ligand Which Are Critical for the Receptor-Ligand Interaction
Biochemistry·1995· 73 cited
Therapeutic effects of a human antiflagella monoclonal antibody in a neutropenic murine model of Pseudomonas aeruginosa pneumonia
Antimicrobial Agents and Chemotherapy·1993· 34 cited
Therapeutic effects of anti flagella and anti lipopolysaccharide lps monoclonal antibodies mabs in neutropenic mice with pseudomonas pneumonia
1991
Generation and characterization of murine antiflagellum monoclonal antibodies that are protective against lethal challenge with Pseudomonas aeruginosa
Infection and Immunity·1990· 50 citedOpen Access
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Frequent Co-authors

Alejandro Aruffo(11), Robert C. Nowinski(5), Michael A. Bowen(5), Diane Hollenbaugh(4), Jürgen Bajorath(4), Gena S. Whitney(3), Gary C. Starling(3), T J Brown(2), Christian P. Larsen(2), Thomas C. Pearson(2), Robert S. Mittler(2), Brett Modrell(2), Steven G. Nadler(2), N. Jan Chalupny(2), John Marken(2), John E. Skonier(2), Marcia N. Gordon(2), Randolph J. Noelle(2), Rolf A. Brekken(2), Gail Workman(2)