Yasuhiko Shinmura

KM Biologics (Japan) — Japan

Immunology and Microbiology · Life Sciences

9h-index313citations20works1.02yr avg
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Research Topics

Poxvirus research and outbreaks(6), Herpesvirus Infections and Treatments(5), Bacillus and Francisella bacterial research(5), Mosquito-borne diseases and control(3), Lymphoma Diagnosis and Treatment(3)

Publications20 total

A phase I, randomized, placebo-controlled, double-blind, ascending-dose and single-center study to evaluate immunogenicity and safety of a live attenuated tetravalent dengue vaccine (KD-382) in Flavivirus antibody-naïve healthy adults
Vaccine·2025· 1 citedOpen Access
Preliminary report: Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, KD-414, in healthy adult participants: a non-randomized, open-label phase 2/3 clinical study in Japan
2022Open Access
Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, KD-414, in healthy adult and elderly subjects: a randomized, double-blind, placebo-controlled, phase 1/2 clinical study in Japan
2022· 5 citedOpen Access
Persistence of neutralizing antibody and its protective efficacy induced by a live attenuated tetravalent dengue vaccine, KD-382, in cynomolgus monkeys
Vaccine·2021· 3 citedOpen Access
Well-balanced immune response and protective efficacy induced by a single dose of live attenuated tetravalent dengue vaccine (KD-382) in monkeys
Heliyon·2020· 6 citedOpen Access
Profiling of the antibody response to attenuated LC16m8 smallpox vaccine using protein array analysis
Vaccine·2019· 9 cited
12-Week Effectiveness and Safety of Low-Density Lipoprotein Cholesterol-Lowering Therapy by Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition in Patients With Familial Hypercholesterolemia and Hypercholesterolemia　― Data From a Real-World Observational Study of Evolocumab in Japan ―
Circulation Reports·2019· 7 citedOpen Access
Safety and efficacy of adalimumab treatment in Japanese patients with psoriasis: Results of <scp>SALSA</scp> study
The Journal of Dermatology·2016· 29 citedOpen Access
Safety of Adalimumab and Predictors of Adverse Events in 1693 Japanese Patients with Crohn’s Disease
Journal of Crohn s and Colitis·2016· 20 citedOpen Access
Freeze-dried live attenuated smallpox vaccine prepared in cell culture “LC16-KAKETSUKEN”: Post-marketing surveillance study on safety and efficacy compliant with Good Clinical Practice
Vaccine·2015· 37 citedOpen Access
Vaccinia virus strain LC16m8 defective in the B5R gene keeps strong protection comparable to its parental strain Lister in immunodeficient mice
Vaccine·2015· 17 citedOpen Access
Reply to “Use of the LC16m8 Smallpox Vaccine in Immunocompromised Individuals Is Still Too Risky”
Clinical and Vaccine Immunology·2015· 8 citedOpen Access
Trend of patient characteristics and its impact on the response to adalimumab in patients with rheumatoid arthritis:<i>post hoc</i>time-course analysis of an all-case PMS in Japan
Modern Rheumatology·2014· 5 cited
Safety of Attenuated Smallpox Vaccine LC16m8 in Immunodeficient Mice
Clinical and Vaccine Immunology·2014· 28 citedOpen Access
FRI0280 Impact of Disease Duration before Starting Adalimumab Treatment on Work Productivity in Japanese Patients with Rheumatoid Arthritis; Analysis of 24-Weeks Data from the Anouveau Study
Annals of the Rheumatic Diseases·2014· 1 cited
Smallpox Vaccine Safety Is Dependent on T Cells and Not B Cells
The Journal of Infectious Diseases·2011· 68 citedOpen Access
O-33 In Vivo Metabolism of 2, 2', 4', 5, 5'-Pentachlorobiphenyl and Its Inductive Activity of Drug-Metabolizing Enzymes : Species Difference between Rats and Mice(Proceedings of the 27th Annual Meeting)
The Journal of Toxicological Sciences·2000
Epstein-Barr virus-specific antibodies in Epstein-Barr virus-positive and -negative gastric carcinoma cases in Japan
Journal of Medical Virology·2000· 48 cited
The induction of hepatic microsomal UDP-glucuronosyltransferase by the methylsulfonyl metabolites of polychlorinated biphenyl congeners in rats
Chemico-Biological Interactions·2000· 21 cited
HIV-1: Entry inhibitors and skin immunization
Japanese Journal of Clinical Immunology·2000Open Access

Frequent Co-authors

Hiroyuki Yokote(5), Kengo Sonoda(5), Hajime Matsui(3), Tomomi Kanehara(3), So Hashizume(3), Yasumasa Nishiyama(2), Yasuhiro Kanatani(2), Hidenori Hase(2), Tsuyoshi Tsuchiya(2), Shinichi Maruno(2), Masahiko Kuranaga(2), Yoshihisa Kato(2), Koichi Haraguchi(2), Yoshito Masuda(2), Ryohei Kimura(2), Masaya Yoshimura(2), Shota Takagi(2), Kazuhisa Kameyama(2), Sutee Yoksan(2), Kazuhiko Kimachi(2)