Christine Debouck

TetraLogic Pharmaceuticals (United States) — United States

Immunology and Microbiology · Life Sciences

49h-index8.5kcitations98works0.02yr avg
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Research Topics

HIV Research and Treatment(53), HIV/AIDS drug development and treatment(37), HIV/AIDS Research and Interventions(10), RNA Research and Splicing(7), RNA Interference and Gene Delivery(7)

Publications98 total

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
Proceedings of the National Academy of Sciences·2010· 306 cited
Integrating genomics across drug discovery and development
Toxicology Letters·2008· 9 cited
Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium‐derived factor: Two novel biomarkers of Alzheimer's disease in human plasma
PROTEOMICS - CLINICAL APPLICATIONS·2008· 56 cited
Proteomics
Encyclopedia of Molecular Cell Biology and Molecular Medicine·2006
Exploiting Model Organisms for Disease Intervention
Encyclopedia of Molecular Cell Biology and Molecular Medicine·2006
Microarrays in Drug Discovery and Development
Encyclopedia of Life Sciences·2006
Interplay of transcriptomics and proteomics.
PubMed·2004· 28 cited
Interplay of transcriptomics and proteomics
Current Opinion in Biotechnology·2003· 228 cited
Further support for the association of CCR5 allelic variants with asthma susceptibility
European Journal of Immunogenetics·2002· 16 cited
Identification, Genomic Organization, and mRNA Expression of LACTB, Encoding a Serine β-Lactamase-like Protein with an Amino-terminal Transmembrane Domain
Genomics·2001· 47 cited
The genome: the beginning, not the end… and a means to many ends
Drug Discovery Today·2001
Construction and applications of gene microarrays on nylon membranes
2000· 1 cited
Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality
Journal of Biological Chemistry·2000· 232 citedOpen Access
The Impact of Genomics on Drug Discovery
The Annual Review of Pharmacology and Toxicology·2000· 118 cited
Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization
Journal of Bone and Mineral Research·1999· 484 citedOpen Access
Expression inEscherichia coli, Refolding, and Purification of Human Procathepsin K, an Osteoclast-Specific Protease
Protein Expression and Purification·1999· 34 cited
DNA microarrays in drug discovery and development
Nature Genetics·1999· 656 cited
The Crystal Structure of Human Procathepsin K
Biochemistry·1998· 82 cited
Functional Characterization of the Protease of Human Endogenous Retrovirus, K10:  Can It Complement HIV-1 Protease?
Biochemistry·1998· 59 cited
Structural Role of the 30's Loop in Determining the Ligand Specificity of the Human Immunodeficiency Virus Protease<sup>,</sup>
Biochemistry·1998· 24 cited
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Frequent Co-authors

Joselina Gorniak(6), James E. Strickler(6), Thomas D. Meek(6), Brian W. Metcalf(5), Martin Rosenberg(5), Maxine Gowen(4), J S Culp(4), Cheryl A. Janson(4), Sherin S. Abdel‐Meguid(4), Jeffrey S. Culp(4), Michael D. Minnich(4), Fred H. Drake(3), Susan B. Richardson(3), Brian D. Hellmig(3), Geoffrey B. Dreyer(3), Michael L. Moore(3), Brian D. Dayton(3), Victoria W. Magaard(3), Ward W. Smith(3), Krishna H. M. Murthy(3)