James A. Scarth

Queen Mary University of London — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index999citations19works7.02yr avg
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Research Topics

DNA Repair Mechanisms(3), Cervical Cancer and HPV Research(3), Cancer-related Molecular Pathways(3), Cardiac Ischemia and Reperfusion(3), Transplantation: Methods and Outcomes(3)

Publications19 total

High levels of DNA replication initiation factors indicate ATRi sensitivity via excessive origin firing
2025· 1 citedOpen Access
Analytical advances in horseracing medication and doping control from 2018 to 2023
Drug Testing and Analysis·2024· 6 cited
The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer
Nature Communications·2024· 20 citedOpen Access
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer
Oncogene·2024· 7 citedOpen Access
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer
2024· 1 citedOpen Access
CREB1 activation promotes human papillomavirus oncogene expression and cervical cancer cell transformation
Journal of Medical Virology·2023· 14 citedOpen Access
Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling
Oncogene·2023· 19 citedOpen Access
Author Reply to Peer Reviews of Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling
2022
Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling
2022· 2 citedOpen Access
Direct sequence confirmation of qPCR products for gene doping assay validation in horses
Drug Testing and Analysis·2022· 9 cited
Screening for gene doping transgenes in horses via the use of massively parallel sequencing
Gene Therapy·2021· 25 cited
The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer
Oncogene·2021· 54 citedOpen Access
The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation
Journal of General Virology·2021· 199 citedOpen Access
E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer
Cell Death and Differentiation·2020· 96 citedOpen Access
Genomic profiling of acute myeloid leukaemia associated with ataxia telangiectasia identifies a complex karyotype with wild‐type <i>TP53</i> and mutant <i>KRAS, G3BP1</i> and <i>IL7R</i>
Pediatric Blood & Cancer·2020· 5 citedOpen Access
Cancer Risks Associated With Germline<i>PALB2</i>Pathogenic Variants: An International Study of 524 Families
Journal of Clinical Oncology·2019· 394 citedOpen Access
Whole Exome Sequencing Identifies Candidate Genes Associated with Hereditary Predisposition to Uveal Melanoma
Ophthalmology·2019· 42 citedOpen Access
PO-061 Exploring heritable predisposition to paediatric rhabdomyosarcomas
ESMO Open·2018· 1 citedOpen Access
Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study
˜The œLancet. Gastroenterology & hepatology·2018· 104 citedOpen Access

Frequent Co-authors

Molly R. Patterson(10), Ethan L. Morgan(10), Andrew Macdonald(10), Christopher W. Wasson(7), Diego Barba‐Moreno(6), Debra Evans(5), Adel Samson(5), James Redman(4), Eleanor Fewings(4), Marc Tischkowitz(4), Miao Wang(4), Adrian Whitehouse(4), Alexey A. Larionov(3), Mae A. Goldgraben(3), Edward J. Ryder(3), Joseph A. Cogan(3), Daisy A. Theobald(3), Holli Carden(3), Jamel Mankouri(3), Emma L. Ryder(3)