Arie Gruzman

University of East Anglia — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index1.8kcitations89works0.82yr avg
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Research Topics

Metabolism, Diabetes, and Cancer(14), Pancreatic function and diabetes(12), Genomics, phytochemicals, and oxidative stress(10), Cardiovascular Function and Risk Factors(6), Amyotrophic Lateral Sclerosis Research(6)

Publications89 total

Medicinal Chemistry Projects Funding in Academia
Chemistry International·2025Open Access
A novel 2-oxopyrrolidine derivative (LN-53) efficiently induces Nrf-2 signaling pathway activation in human epidermal keratinocytes
Pharmacological Reports·2025· 1 citedOpen Access
Evaluation of the Recent Dynamics for Funding Medicinal Chemistry Projects in Academia. Results of a Survey Conducted by IUPAC Division VII (Chemistry and Human Health)
Journal of Medicinal Chemistry·2025
A Unified Synthesis of Electron-Deficient 1,4- and 1,1,4-Substituted 1,3-Dienes through a Base-Promoted Allylation Followed by <i>Retro</i>-Michael Vinylogous Dehydrosulfinylation
Organic Letters·2024· 3 cited
P14-06 The cytotoxicity of bortezomib in AC16 cardiac cells and possible therapeutic options involving Nrf2
Toxicology Letters·2024Open Access
Moderately lipophilic 2-(Het)aryl-6-dithioacetals, 2-phenyl-1,4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators
Bioorganic & Medicinal Chemistry·2023
A Novel Facial Cream Based on Skin Penetrable Hemp Oil Microparticles
Journal of Cosmetics Dermatological Sciences and Applications·2023· 3 citedOpen Access
4-Phenylbutyric Acid (4-PBA) Derivatives Prevent SOD1 Amyloid Aggregation In Vitro with No Effect on Disease Progression in SOD1-ALS Mice
International Journal of Molecular Sciences·2022· 8 citedOpen Access
NRF2 in dermatological disorders: Pharmacological activation for protection against cutaneous photodamage and photodermatosis
Free Radical Biology and Medicine·2022· 35 citedOpen Access
CCDC 2053535: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
CCDC 2053534: Experimental Crystal Structure Determination
The Cambridge Structural Database·2022Open Access
Straightforward Access to Terminally Disubstituted Electron‐Deficient Alkylidene Cyclopent‐2‐en‐4‐ones through Olefination with α‐Carbonyl and α‐Cyano Secondary Alkyl Sulfones
European Journal of Organic Chemistry·2021· 1 cited
SH-29 and SK-119 Attenuates Air-Pollution Induced Damage by Activating Nrf2 in HaCaT Cells
International Journal of Environmental Research and Public Health·2021· 16 citedOpen Access
Development of anti-inflammatory peptidomimetics based on the structure of human alpha1-antitrypsin
European Journal of Medicinal Chemistry·2021· 5 cited
Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator
Molecular Diversity·2021· 3 cited
Multifunctionality of Prostatic Acid Phosphatase in Prostate  Cancer Pathogenesis
Bioscience Reports·2021· 5 citedOpen Access
Multifunctionality of prostatic acid phosphatase in prostate cancer pathogenesis
Bioscience Reports·2021· 13 citedOpen Access
A Potent Leukocyte Transmigration Blocker: GT-73 Showed a Protective Effect against LPS-Induced ARDS in Mice
Molecules·2021· 6 citedOpen Access
Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy
Journal of Medicinal Chemistry·2021· 17 citedOpen Access
Investigation of the Membrane Fluidity Regulation of Fatty Acid Intracellular Distribution by Fluorescence Lifetime Imaging of Novel Polarity Sensitive Fluorescent Derivatives
International Journal of Molecular Sciences·2021· 27 citedOpen Access
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Frequent Co-authors

Shlomo Sasson(21), Guy Cohen(14), Evgenia Alpert(12), Shirin Kahremany(11), Olga Viskind(9), Hanoch Senderowitz(9), Jürgen Eckel(6), Erol Cerasi(5), Laura M. Levy(4), Lukas Hofmann(4), Salome Azoulay‐Ginsburg(4), Edward E. Korshin(4), Anna Munder(4), Sharon Ruthstein(4), Ella Meltzer-Mats(3), Tamar Getter(3), Yael Riahi(3), Hana Totary-Jain(3), Reuven Reich(3), Tali Ben‐Zur(3)