Juan Carlos Izpisúa Belmonte

Fleet Science Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

123h-index52.5kcitations585works13.92yr avg
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Research Topics

Pluripotent Stem Cells Research(228), CRISPR and Genetic Engineering(184), Developmental Biology and Gene Regulation(63), Congenital heart defects research(59), Epigenetics and DNA Methylation(57)

Publications584 total

Vascular organoid model of Hutchinson-Gilford progeria syndrome uncovers repression of the SRF pathway in premature aging
Developmental Cell·2025
Nuclear-lamin-guided plastic positioning and folding of the human genome
Cell Reports·2025Open Access
Vitamin C conveys geroprotection on primate ovaries
Cell stem cell·2025· 2 cited
Gene Editing Nuclear and Mitochondrial DNA
Elsevier eBooks·2025
Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming
Cell·2025· 18 cited
EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework
GeroScience·2025· 2 citedOpen Access
Escaping ageing through Cell Annealing—a phenomenological model
Cell Research·2025· 2 citedOpen Access
Author Correction: PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
Nature Communications·2025Open Access
Single-cell profiling identifies hair cell SLC35F1 deficiency as a signature of primate cochlear aging
Nature Aging·2025· 8 cited
Author Correction: Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
Nature·2025
Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models
Science Translational Medicine·2025· 6 cited
Reactivation of retrotransposable elements is associated with environmental stress and ageing
Nature Reviews Genetics·2025· 19 cited
Dynamic WNT signaling controls differentiation of hematopoietic progenitor cells from human pluripotent stem cells
Science China Life Sciences·2025· 2 citedOpen Access
Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants
Cell Genomics·2025· 24 citedOpen Access
Author Correction: SGF29 nuclear condensates reinforce cellular aging
Cell Discovery·2025Open Access
Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation
STAR Protocols·2025· 2 citedOpen Access
Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
Cell stem cell·2025· 1 cited
A single-cell transcriptomic atlas of exercise-induced anti–inflammatory and geroprotective effects across the body
The Innovation·2025Open Access
CELL REJUVENATION AND DISEASE
Innovation in Aging·2024Open Access
Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa
Investigative Ophthalmology & Visual Science·2024· 3 citedOpen Access
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Frequent Co-authors

Concepción Rodrı́guez Esteban(16), Guang‐Hui Liu(10), Keiichiro Suzuki(9), Jing Qu(9), Stéphanie Boué(7), Weiqi Zhang(7), Ángel Raya(6), Jun Wu(6), Mo Li(6), Josep M. Campistol(6), María J. Barrero(5), Núria Montserrat(5), Sergio Ruiz(5), Javier Capdevila(5), Trond Aasen(4), Federico Gonzãlez(4), Rita Vassena(4), Athanasia D. Panopoulos(4), Kun Zhang(4), Tomoaki Hishida(4)