Andrey A. Bobkov

Sanford Burnham Prebys Medical Discovery Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.9kcitations97works1.62yr avg
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Research Topics

Cellular Mechanics and Interactions(14), Cardiomyopathy and Myosin Studies(13), ATP Synthase and ATPases Research(13), Cancer, Hypoxia, and Metabolism(9), Protein Structure and Dynamics(8)

Publications97 total

Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure
2026Open Access
Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure
SSRN Electronic Journal·2026Open Access
Structural basis for lipid binding by the blood protein vitronectin, a component of HDL
2025Open Access
CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk
2025· 3 citedOpen Access
Incorporating Metal–Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers
Biochemistry·2025
Structural diversity and oligomerization of bacterial ubiquitin-like proteins
Structure·2025· 4 cited
Synergistic RAS-MAPK and AKT Activation in MYC-Driven Tumors via Adjacent PVT1 Rearrangements
2025· 1 citedOpen Access
Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor
Structure·2025· 4 cited
Fragment Screening Identifies Novel Allosteric Binders and Binding Sites in the VHR (<i>DUSP3</i>) Phosphatase
ACS Omega·2025· 6 citedOpen Access
LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis
2025· 1 citedOpen Access
Structural diversity and oligomerization of bacterial ubiquitin-like proteins
2024· 3 citedOpen Access
Structural Basis for Substrate Binding, Catalysis and Inhibition of Breast Cancer Target Mitochondrial Creatine Kinase by Covalent Inhibitor via Cryo-EM
2024Open Access
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms
Nature Communications·2024· 3 citedOpen Access
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms
Research Square (Research Square)·2024Open Access
Engineering gain-of-function mutants of a WW domain by dynamics and structural analysis
Biophysical Journal·2024Open Access
Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms
2024· 1 citedOpen Access
Engineering gain‐of‐function mutants of a <scp>WW</scp> domain by dynamics and structural analysis
Protein Science·2023· 6 citedOpen Access
TMEM2 is a bona fide hyaluronidase possessing intrinsic catalytic activity
Journal of Biological Chemistry·2023· 21 citedOpen Access
Data from Molecular Inhibitor of QSOX1 Suppresses Tumor Growth &lt;i&gt;In Vivo&lt;/i&gt;
2023Open Access
Data from Molecular Inhibitor of QSOX1 Suppresses Tumor Growth &lt;i&gt;In Vivo&lt;/i&gt;
2023Open Access
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Frequent Co-authors

Robert Liddington(11), Emil Reisler(9), Laurie A. Bankston(7), Francesca M. Marassi(6), Alexander E. Aleshin(5), Yuanyuan Yao(5), Dmitrii I. Levitsky(5), G. Cadwell(4), Mark H. Ginsberg(4), András Mühlrád(4), David R. Critchley(3), L. Miya Fujimoto(3), Alexandre R. Gingras(3), Elena Bobkova(3), Lester J. Lambert(3), Giovanna Ghirlanda(3), Constantina Bakolitsa(2), Lisa K. Jennings(2), Kenneth A. Taylor(2), Igor Barsukov(2)