Andrew D. Miranker

Yale University — United States

Medicine · Health Sciences

43h-index7.8kcitations104works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(48), Protein Structure and Dynamics(47), Supramolecular Self-Assembly in Materials(21), Enzyme Structure and Function(16), Lipid Membrane Structure and Behavior(12)

Publications104 total

African Green Monkeys Respond to Synthetic Aβ Oligomers with Persistent Alzheimer’s-like Activation
2025Open Access
Assessing and mitigating privacy risks of sparse, noisy genotypes by local alignment to haplotype databases
Genome Research·2023· 2 citedOpen Access
Assessing and mitigating privacy risk of sparse, noisy genotypes by local alignment to haplotype databases
2021· 2 citedOpen Access
Data Sanitization to Reduce Private Information Leakage from Functional Genomics
Cell·2020· 39 citedOpen Access
STEM Climate survey developed through student–faculty collaboration
Teaching in Higher Education·2019· 11 cited
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein
PLoS Biology·2019· 51 citedOpen Access
α-Synuclein Binds Extracellular Complex N-Linked Glycans
Biophysical Journal·2019Open Access
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein
2018Open Access
Private information leakage from functional genomics data: Quantification with calibration experiments and reduction via data sanitization protocols
2018· 6 citedOpen Access
Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid
Nature Communications·2018· 61 citedOpen Access
Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands
Methods in enzymology on CD-ROM/Methods in enzymology·2018· 20 cited
Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide
Biophysical Journal·2017Open Access
Structurally distinct oligomers of islet amyloid polypeptide mediate toxic and non-toxic membrane poration
2016Open Access
Foldamer-mediated manipulation of a pre-amyloid toxin
Nature Communications·2016· 76 citedOpen Access
Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies
Langmuir·2016· 10 cited
Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin
Chemical Communications·2016· 26 citedOpen Access
Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes
Journal of Diabetes Research·2015· 10 citedOpen Access
A solenoid design for assessing determinants of parallel  -sheet registration
Protein Engineering Design and Selection·2015Open Access
Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry
The Journal of Physical Chemistry B·2015· 8 cited
Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity
Biochemistry·2015· 11 citedOpen Access
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Frequent Co-authors

Christopher M. Dobson(7), James A. Hebda(7), Elizabeth Rhoades(7), Carol V. Robinson(5), Sheena E. Radford(5), Catherine M. Eakin(5), Ishu Saraogi(5), Andrew D. Hamilton(5), Sunil Kumar(5), Jefferson D. Knight(4), Matthew F. Calabrese(4), Charles J. Morgan(4), Martin Karplus(3), Abhinav Nath(3), Jessica A. Williamson(3), Nicholas B. Last(3), Mazin Magzoub(3), Diana E. Schlamadinger(3), Melissa Birol(3), Shae B. Padrick(2)