Alejandro Panjkovich

European Molecular Biology Laboratory — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index3.7kcitations35works2.02yr avg
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Research Topics

Protein Structure and Dynamics(12), Enzyme Structure and Function(10), Computational Drug Discovery Methods(5), Glycosylation and Glycoproteins Research(4), Statistical Methods in Clinical Trials(4)

Publications35 total

Studies of the structural properties and stability of the molybdenum transport protein ModA from Oleidesulfovibrio alaskensis G20 upon metal binding
Archives of Biochemistry and Biophysics·2025
Synergistic Activity of BMS-986397, a First-in-Class a Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Targeting Casein Kinase 1α (CK1α), in Combination with Venetoclax and/or Azacitidine in Preclinical Models of Acute Myeloid Leukemia (AML)
Blood·2024Open Access
Structural insights of an LCP protein–LytR–from Streptococcus dysgalactiae subs. dysgalactiae through biophysical and in silico methods
Frontiers in Chemistry·2024· 6 citedOpen Access
Drug representation and scrambling experiments highlight issues with training and evaluation of drug-target interaction predictive models
2022
Drug representation and scrambling experiments highlight issues with training and evaluation of drug-target interaction predictive models
2022
Drug representation and scrambling experiments highlight issues with training and evaluation of drug-target interaction predictive models
2022
Drug representation and scrambling experiments highlight issues with training and evaluation of drug-target interaction predictive models
2022
Abstract 3932: Pathway interaction and mechanistic synergy of CC-99282, a novel cereblon E3 ligase modulator (CELMoD) agent, with enhancer of zeste homolog 2 inhibitors (EZH2is)
Cancer Research·2022· 2 cited
Improving the Assessment of Deep Learning Models in the Context of Drug-Target Interaction Prediction
2022· 3 citedOpen Access
<i>ATSAS 3.0</i>: expanded functionality and new tools for small-angle scattering data analysis
Journal of Applied Crystallography·2020· 977 citedOpen Access
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
Nature Communications·2020· 44 citedOpen Access
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms
2019· 3 citedOpen Access
Shedding Light on the Interaction of Human Anti-Apoptotic Bcl-2 Protein with Ligands through Biophysical and in Silico Studies
International Journal of Molecular Sciences·2019· 31 citedOpen Access
CHROMIXS: automatic and interactive analysis of chromatography-coupled small-angle X-ray scattering data
Bioinformatics·2017· 314 citedOpen Access
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Nature Communications·2017· 54 citedOpen Access
<i>ATSAS 2.8</i> software for small-angle scattering from macromolecular solutions
Acta Crystallographica Section A Foundations and Advances·2017Open Access
SASBDB and <i>DARA</i> as biological solution-scattering teaching tools
Acta Crystallographica Section A Foundations and Advances·2017Open Access
Integrating SEC-SAXS with MALLS/QELS/RI at the EMBL-P12 bioSAXS beamline
Acta Crystallographica Section A Foundations and Advances·2017Open Access
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20
Scientific Reports·2017· 16 citedOpen Access
<i>ATSAS 2.8</i>: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions
Journal of Applied Crystallography·2017· 1.4k citedOpen Access
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Frequent Co-authors

Dmitri I. Svergun(16), Mirko Torrisi(5), Daniel Franke(4), Haydyn D. T. Mertens(4), Alexey Kikhney(4), Cy M. Jeffries(4), Xavier Daura(4), Teresa Santos‐Silva(4), de la Vega de Leon Antonio(4), Maxim V. Petoukhov(3), Petr V. Konarev(3), Nelly R. Hajizadeh(3), Francisco Melo(3), Patrick Aloy(3), Sandrine Georgeon(3), Tim Kükenshöner(3), Florence Pojer(3), Oliver Hantschel(3), M.A.S. Correia(3), Anne Tuukkanen(2)