Libert H.K. Defize

University of Applied Sciences Utrecht — Netherlands

Medicine · Health Sciences

28h-index5.0kcitations56works0.02yr avg
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Research Topics

HER2/EGFR in Cancer Research(12), Protein Kinase Regulation and GTPase Signaling(10), Monoclonal and Polyclonal Antibodies Research(10), Bone health and treatments(7), Pluripotent Stem Cells Research(6)

Publications56 total

Dawn of the organoid era
BioEssays·2017· 62 citedOpen Access
Calcium in the Action of Growth Factors
Novartis Foundation symposium·2007· 13 cited
Twenty one years of P19 cells: what an embryonal carcinoma cell line taught us about cardiomyocyte differentiation
Cardiovascular Research·2003· 189 cited
The defective transforming phenotype of c-Jun Ala63/73 is rescued by mutation of the C-terminal phosphorylation site
Oncogene·2001· 6 cited
Cloning and analysis of the mouse follistatin promoter
Molecular Biology Reports·2000· 20 cited
Dynamic connexin43 expression and gap junctional communication during endoderm differentiation of F9 embryonal carcinoma cells
European Journal of Cell Biology·2000· 11 cited
Snail is an immediate early target gene of parathyroid hormone related peptide signaling in parietal endoderm formation
The International Journal of Developmental Biology·2000· 51 citedOpen Access
Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells
Oncogene·1999· 29 citedOpen Access
Identification of a Retinoic Acid-Inducible Element in the Murine PTH/PTHrP (Parathyroid Hormone/Parathyroid Hormone-Related Peptide) Receptor Gene
Molecular Endocrinology·1999· 17 cited
Parathyroid hormone-related peptide (PTHrP) induces parietal endoderm formation exclusively via the Type I PTH/PTHrP receptor
Mechanisms of Development·1999· 26 cited
The Ras/Erk Pathway Induces Primitive Endoderm but Prevents Parietal Endoderm Differentiation of F9 Embryonal Carcinoma Cells
Journal of Biological Chemistry·1999· 53 citedOpen Access
Signals governing extraembryonic endoderm formation in the mouse: involvement of the type 1 parathyroid hormone-related peptide (PTHrP) receptor, p21Ras and cell adhesion molecules
The International Journal of Developmental Biology·1999· 36 citedOpen Access
Growth factor signalling
The International Journal of Developmental Biology·1999· 11 citedOpen Access
Identification of connexin43 as a functional target for Wnt signalling
Journal of Cell Science·1998· 212 cited
Expression of the Parathyroid Hormone-Related Peptide Gene in Retinoic Acid-Induced Differentiation: Involvement of ETS and Sp1
Molecular Endocrinology·1997· 27 citedOpen Access
Tissue-Specific Transcription Start Sites and Alternative Splicing of the Parathyroid Hormone (PTH)/PTH-Related Peptide (PTHrP) Receptor Gene: A New PTH/PTHrP Receptor Splice Variant that Lacks the Signal Peptide*
Endocrinology·1997· 79 cited
Parathyroid Hormone Activates Mitogen-activated Protein Kinase via a cAMP-mediated Pathway Independent of Ras
Journal of Biological Chemistry·1997· 90 citedOpen Access
PTH/PTHrP Receptor in Early Development and Indian Hedgehog—Regulated Bone Growth
Science·1996· 1.3k cited
Parathyroid hormone related peptide mRNA expression during murine postimplantation development: evidence for involvement in multiple differentiation processes
The International Journal of Developmental Biology·1996· 53 citedOpen Access
Epidermal Growth Factor (EGF) Induces Serine Phosphorylation‐Dependent Activation and Calcium‐Dependent Translocation of the Cytosolic Phospholipase A<sub>2</sub>
European Journal of Biochemistry·1995· 59 cited
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Frequent Co-authors

Siegfried W. de Laat(22), Wouter H. Moolenaar(10), J. Boonstra(10), Marcel Karperien(9), Abdul‐Badi Abou‐Samra(6), Johannes Boonstra(6), Mark H. G. Verheijen(6), Beate Lanske(5), Ben C. Tilly(5), Marcel Spaargaren(5), A. J. Bierman(4), Paul M.P. van Bergen en Henegouwen(4), Clemens W.G.M. Löwik(4), Arie J. Verkleij(4), Paul T. van der Saag(4), Jacqueline M. Veltmaat(4), Harald Jüppner(3), Henry M. Kronenberg(3), Tony Hunter(3), Marcel A. G. van der Heyden(3)