Patricia Busto

University of Massachusetts Chan Medical School — United States

Immunology and Microbiology · Life Sciences

13h-index1.5kcitations23works0.02yr avg
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Research Topics

Immune Response and Inflammation(9), T-cell and B-cell Immunology(8), Immune Cell Function and Interaction(8), interferon and immune responses(7), Monoclonal and Polyclonal Antibodies Research(5)

Publications23 total

Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells
The Journal of Immunology·2019· 2 citedOpen Access
Role of Interferon‐γ–Producing Th1 Cells in a Murine Model of Type I Interferon–Independent Autoinflammation Resulting From <scp>DN</scp>ase <scp>II</scp> Deficiency
Arthritis & Rheumatology·2019· 12 citedOpen Access
Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma
The Journal of Immunology·2016· 62 citedOpen Access
Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?
Journal of Leukocyte Biology·2016· 13 citedOpen Access
TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
The Journal of Immunology·2016· 65 citedOpen Access
Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II−/−IFNaR−/− Mice
The Journal of Immunology·2016· 12 citedOpen Access
An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.
PubMed·2015· 5 citedOpen Access
Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses
The Journal of Immunology·2015· 68 citedOpen Access
Cutting Edge: DNase II Deficiency Prevents Activation of Autoreactive B Cells by Double-Stranded DNA Endogenous Ligands
The Journal of Immunology·2015· 52 citedOpen Access
Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II–Deficient Mice
The Journal of Immunology·2014· 102 citedOpen Access
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Nature Immunology·2014· 740 citedOpen Access
Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus
The Journal of Immunology·2013· 20 citedOpen Access
The role of Bruton's tyrosine kinase in the development and BCR/TLR-dependent activation of AM14 rheumatoid factor B cells
Journal of Leukocyte Biology·2013· 14 citedOpen Access
Selective binding of anti-DNA antibodies to native dsDNA fragments of differing sequence
Immunology Letters·2012· 22 cited
Systemic Lupus Erythematosus Fc{gamma}RIIB-/- Mouse Models of Fc{gamma}RIIB-/-Yaa and for Disease Development in the IFN Regulatory Factor 5 Is Required
2010
IFN Regulatory Factor 5 Is Required for Disease Development in the <i>FcγRIIB−/−Yaa</i> and <i>FcγRIIB−/−</i> Mouse Models of Systemic Lupus Erythematosus
The Journal of Immunology·2009· 94 citedOpen Access
Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-α
The Journal of Immunology·2008· 82 citedOpen Access
Alternative delivery of keratinocytes using a polyurethane membrane and the implications for its use in the treatment of full-thickness burn injury
Burns·1998· 123 cited
Endogenous Ig production in mu transgenic mice. I. Allelic exclusion at the level of expression
The Journal of Immunology·1993· 8 cited
Anti-idiotypic antibodies function as a surrogate surface epitope of Brugia malayi infective larvae
Acta Tropica·1990· 5 cited
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Frequent Co-authors

Ann Marshak‐Rothstein(16), Kerstin Nündel(9), Katherine A. Fitzgerald(5), Ellen M. Gravallese(5), Sudesh Pawaria(5), Rebecca Baum(4), Ramon Bonegio(4), Lukas Bossaller(3), Eicke Latz(3), Shruti Sharma(3), Krishna Moody(3), Quan‐Zhen Li(2), Christophe Richez(2), Kei Yasuda(2), Amanda A. Watkins(2), Tamar Aprahamian(2), Rocco J. Richards(2), Regina Cheung(2), Ian R. Rifkin(2), Melissa B. Uccellini(2)