Shenghai Chang

Sir Run Run Shaw Hospital — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index3.3kcitations58works8.22yr avg
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Research Topics

Ion channel regulation and function(12), Bacterial Genetics and Biotechnology(8), Neuroscience and Neuropharmacology Research(7), RNA and protein synthesis mechanisms(7), Antibiotic Resistance in Bacteria(6)

Publications58 total

Deciphering the molecular mechanism of the bacterial division motor TolQRA
Cell Discovery·2025· 2 citedOpen Access
Tribological enhancement of seal blocks using petrochemical diesel carbonaceous particles
Journal of Physics Conference Series·2025Open Access
High-resolution structure of the heat-stable form-IAq RuBisCO from the thermophilic purple sulfur bacterium Thermochromatium tepidum
Scientific Reports·2025· 1 citedOpen Access
Molecular basis of β-arrestin coupling to the metabotropic glutamate receptor mGlu3
Nature Chemical Biology·2025· 10 cited
Ultrahigh Resolution Structure of the Heat-stable Form-IAq RuBisCO from the Thermophilic Purple Sulfur Bacterium <i>Thermochromatium tepidum</i>
2025Open Access
Dynamics of the mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis
Nature Communications·2025· 10 citedOpen Access
Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase
Nature Structural & Molecular Biology·2025· 9 citedOpen Access
Structural insights into the activation mechanism of the human zinc-activated channel
Nature Communications·2025· 1 citedOpen Access
Deciphering the molecular basis of lipoprotein recognition and transport by LolCDE
Signal Transduction and Targeted Therapy·2024· 6 citedOpen Access
Structural insights into the mechanotransducing mechanism of FtsEX in cell division
MedComm·2024· 6 citedOpen Access
An inhibitory mechanism of AasS, an exogenous fatty acid scavenger: Implications for re-sensitization of FAS II antimicrobials
PLoS Pathogens·2024· 8 citedOpen Access
Architecture of intact mammalian pyruvate dehydrogenase complex revealed by <i>in-situ</i> structural analysis
2024· 1 citedOpen Access
Structural basis for sugar perception by <i>Drosophila</i> gustatory receptors
Science·2024· 52 cited
Structural insights into the activation of the divisome complex FtsWIQLB
Cell Discovery·2024· 9 citedOpen Access
Dynamic topology-mediated maturation of β-barrel proteins in BAM-catalyzed folding
2023Open Access
Molecular basis of Mg2+ permeation through the human mitochondrial Mrs2 channel
Nature Communications·2023· 23 citedOpen Access
Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel
Cell Discovery·2023· 14 citedOpen Access
Structural basis of BAM-mediated outer membrane β-barrel protein assembly
Nature·2023· 80 cited
Structures of the human Wilson disease copper transporter ATP7B
Cell Reports·2023· 49 citedOpen Access
Publisher Correction: Structures and mechanisms of the Arabidopsis auxin transporter PIN3
Nature·2022· 3 citedOpen Access
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Frequent Co-authors

Xing Zhang(24), Xiaodi Tang(9), Haohao Dong(9), Jiangtao Guo(7), Qinghua Luo(7), Tianlei Wen(7), Xuhang Lu(7), Yuequan Shen(7), Xue Yang(7), Hangjun Wu(6), Haichun Gao(5), Qiao Wen(5), Changbin Zhang(5), Xiaofeng Zhu(5), Xiawei Wei(5), Changjiang Dong(5), Chongrong Shen(5), Chen Wang(5), Cheng Zhao(4), Fan Yang(4)