Guihai Feng

California Institute for Regenerative Medicine — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index5.4kcitations98works9.12yr avg
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Research Topics

CRISPR and Genetic Engineering(32), Pluripotent Stem Cells Research(25), Epigenetics and DNA Methylation(13), Single-cell and spatial transcriptomics(11), Cancer-related molecular mechanisms research(10)

Publications97 total

High-efficiency generation of blastoids with gastrulation potential through Gata4-induced PrE specification in mESCs
Cell Discovery·2025Open Access
De-extinction and beyond: trait design powered by generative AI
Trends in biotechnology·2025
Phase 1 dose-escalation trial of sub-endometrial injection of human embryonic stem cells-derived immunity-and-matrix-regulatory cells to promote endometrial angiogenesis in refractory intrauterine adhesion
Molecular Therapy·2025Open Access
Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples (Adv. Sci. 35/2025)
Advanced Science·2025Open Access
Achieving scalable expansion of therapeutic porcine hepatocytes in vivo through serial transplantation
Animal Models and Experimental Medicine·2025Open Access
FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples
Advanced Science·2025Open Access
KIAA1522 isoform switching regulates LTR-RTs activity in distinct pluripotency states of hESCs
Science China Life Sciences·2025· 1 cited
Sequence and parent-of-origin dependent m6A contribute to allele-specific gene expression
The EMBO Journal·2025· 3 citedOpen Access
<scp>NSun2</scp>‐Mediated <scp>tsRNAs</scp> Alleviate Liver Fibrosis via <scp>FAK</scp> Dephosphorylation
Cell Proliferation·2025· 4 citedOpen Access
scCompass: An Integrated Multi‐Species scRNA‐seq Database for AI‐Ready
Advanced Science·2025· 7 citedOpen Access
Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals
Cell stem cell·2025· 11 citedOpen Access
Miltefosine reinvigorates exhausted T cells by targeting their bioenergetic state
Cell Reports Medicine·2024· 4 citedOpen Access
scCompass: An integrated cross-species scRNA-seq database for AI-ready
2024· 5 citedOpen Access
How Do Large Language Models Understand Genes and Cells
ACM Transactions on Intelligent Systems and Technology·2024· 2 citedOpen Access
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model
Cell Research·2024· 78 citedOpen Access
All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposons
Cell·2024· 26 citedOpen Access
Elimination of <scp><i>GGTA1</i></scp>, <scp><i>CMAH</i></scp>, <scp><i>β4GalNT2</i></scp> and <scp><i>CIITA</i></scp> genes in pigs compromises human versus pig xenogeneic immune reactions
Animal Models and Experimental Medicine·2024· 6 citedOpen Access
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Cell Proliferation·2024Open Access
Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro
Cell stem cell·2024· 2 cited
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Frequent Co-authors

Qi Zhou(35), Wei Li(26), Liu Wang(13), Jiaqiang Wang(12), Leyun Wang(12), Haifeng Wan(11), Baoyang Hu(11), Kai Xu(10), Jie Hao(10), Ying Zhang(9), Tianda Li(8), Qi Gu(8), Lu Guo(7), Yukai Wang(7), Wei Li(7), Liyuan Jiang(6), Xiu‐Jie Wang(6), Yuhuan Li(6), Tongtong Cui(6), Zhikun Li(6)