Kostiantyn P. Melnykov

Taras Shevchenko National University of Kyiv — UA

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

15h-index813citations94works1.92yr avg
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Research Topics

Fluorine in Organic Chemistry(48), Chemical Synthesis and Analysis(22), Synthesis and Reactions of Organic Compounds(16), Crystallization and Solubility Studies(11), X-ray Diffraction in Crystallography(11)

Publications92 total

α-Fluoroalkyl-substituted cyclopentane building blocks for drug discovery
Journal of Fluorine Chemistry·2026
Physicochemical Properties of α-Fluoroalkyl-Substituted Cycloalkylamines and Amino Acids
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Physicochemical Properties of α-Fluoroalkyl-Substituted Cycloalkylamines and Amino Acids
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Physicochemical Properties of α-Fluoroalkyl-Substituted Cycloalkylamines and Amino Acids
2026Open Access
Synthesis and Physicochemical Properties of trans-2-Fluoroalkyl-Substituted Cyclopentane Building Blocks
2026Open Access
Synthesis of Multifunctional 2,3‐Dihydroquinolin‐4(1 <i>H</i> )‐one Building Blocks via Permanganate‐Promoted Oxidation of 1,2,3,4‐Tetrahydroquinolines
ChemistrySelect·2026
α-Fluoroalkyl-Substituted Cyclopentane Building Blocks for Drug Discovery
2025
Front Cover: Basicity and Lipophilicity of <i>gem</i> ‐Difluorinated Saturated Bicyclic Amines: Advanced Building Blocks for Drug Discovery (Eur. J. Org. Chem. 45/2025)
European Journal of Organic Chemistry·2025Open Access
Synthesis of Multifunctional 2,3-Dihydroquinolin-4(1H)-one Building Blocks via Permanganate-Promoted Oxidation of 1,2,3,4-Tetrahydroquinolines
2025
Gram-scale synthesis and physicochemical properties of exo- and endo-5,5-difluorooctahydropentalen-2-amines
Journal of Fluorine Chemistry·2025
Gram-Scale Synthesis and Physicochemical Properties of exo- and endo-5,5-Difluorooctahydropentalen-2-amines
2025Open Access
Basicity and Lipophilicity of <i>gem</i> ‐Difluorinated Saturated Bicyclic Amines: Advanced Building Blocks for Drug Discovery
European Journal of Organic Chemistry·2025· 3 citedOpen Access
Physicochemical Properties of gem-Difluorinated Saturated Bicyclic Amines – Advanced Building Blocks for Drug Discovery
2025· 1 citedOpen Access
Machine Learning-Based Retention Time Prediction Tool for Routine LC-MS Data Analysis
Journal of Chemical Information and Modeling·2025
Scalable DOS-like Strategy to the δ-Amino Acids via Petasis/Cross Metathesis Reactions Sequence
The Journal of Organic Chemistry·2025
DOS‐Like Strategy for the Spirocyclic MedChem Relevant Building Blocks via Petasis / Grubbs Reactions Sequence
Chemistry - A European Journal·2025· 2 citedOpen Access
Scalable DOS-like Strategy to the δ-Amino Acids via Petasis/Cross Metathesis Reactions Sequence
2025· 2 citedOpen Access
Machine Learning-Based Retention Time Prediction Tool for Routine LC-MS Data Analysis
2025Open Access
DOS-like strategy for the spirocyclic MedChem relevant building blocks via Petasis / Grubbs reactions sequence
2025· 1 citedOpen Access
Filling the Gap in LogP$$ LogP $$ and pKa$$ {pK}_a $$ Evaluation for Saturated Fluorine‐Containing Derivatives With Machine Learning
Journal of Computational Chemistry·2025Open Access
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Frequent Co-authors

Oleksandr O. Grygorenko(40), Dmitriy M. Volochnyuk(23), Sergey V. Ryabukhin(18), Oleksandr S. Liashuk(14), Serhii Holovach(10), Petro Borysko(10), Мaksym Herasymchuk(9), Oleh Smyrnov(8), Dmytro Lesyk(8), Bohdan V. Vashchenko(7), Yuliia Holota(7), Oleksandr P. Demchuk(5), Artem Skreminskiy(5), Alexander B. Rozhenko(5), Oleksandr V. Hryshchuk(5), Ivan S. Kondratov(4), Eugeniy N. Ostapchuk(4), Rustam T. Iminov(4), Illia Poroshyn(4), Dmytro Dudenko(4)