Chad A. Mirkin

Northwestern University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

182h-index161.7kcitations1.7kworks7.12yr avg
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Research Topics

Advanced biosensing and bioanalysis techniques(533), Gold and Silver Nanoparticles Synthesis and Applications(377), Crystallization and Solubility Studies(255), X-ray Diffraction in Crystallography(251), RNA Interference and Gene Delivery(199)

Publications1.7k total

E7 <sub>11-19</sub> placement and orientation dictate CD8 <sup>+</sup> T cell response in structurally defined spherical nucleic acid vaccines
Science Advances·2026Open Access
Image processing pipeline for AI-driven nanoparticle megalibrary characterization
Scientific Reports·2026Open Access
Amphiphilic Polymeric Micelle Spherical Nucleic Acids (SNAs) as Drug Delivery Vehicles
Bioconjugate Chemistry·2025
Discovering Complex Metal Chalcogenide Nanostructures through Nanoreactor-Mediated Synthesis
Journal of the American Chemical Society·2025Open Access
Colloidal Crystals Engineered with DNA from Supramolecular Programmable Atom Equivalents with Stimuli-Responsive Cores
Journal of the American Chemical Society·2025
Electroreductive Synthesis of Long Chain Fatty Alcohols from CO <sub>2</sub>
ECS Meeting Abstracts·2025
cGAS-agonistic spherical nucleic acids reprogram the glioblastoma immune microenvironment and promote antitumor immunity
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Controlling intracellular processing to enhance spherical nucleic acid immune stimulation
Proceedings of the National Academy of Sciences·2025Open Access
Structural immunotherapy: Harnessing chemical design to build powerful next-generation therapeutics
Proceedings of the National Academy of Sciences·2025Open Access
911 Facial intradermal administration: a novel brain targeting strategy with immune-modulating cGAS-STING and STAT3 bimodal spherical nucleic acids for anti-glioma effect
Regular and Young Investigator Award Abstracts·2025Open Access
Chemotherapeutic Spherical Nucleic Acids
ACS Nano·2025· 1 citedOpen Access
Inverse Design of DNA-Programmable Protein Colloidal Crystals
Journal of the American Chemical Society·2025
Modular Supramolecular Assembly through Clickable Hemilabile Ligands via the Weak-Link Approach
Inorganic Chemistry·2025· 1 cited
Cleavable Hydrophobic Anchors Optimize Immunomodulatory Effects of Oligonucleotides
Journal of the American Chemical Society·2025· 1 citedOpen Access
A-Cation-Dependent Structure–Optical Property Relationships of Halide Perovskite Heterostructures with Complex Interfaces
Journal of the American Chemical Society·2025
Enhanced spectral purity of WSe <sub>2</sub> quantum emitters via conformal organic adlayers
Science Advances·2025· 1 citedOpen Access
Polyelemental Nanoparticle Synthesis Enabled by Noncontact Metallothermic Reactions
Journal of the American Chemical Society·2025
Salt-Induced Polymorphs Observed in Colloidal Single Crystals
Journal of the American Chemical Society·2025
33 Unresolved Questions in Nanoscience and Nanotechnology
ACS Nano·2025· 13 citedOpen Access
A general genome editing strategy using CRISPR lipid nanoparticle spherical nucleic acids
Proceedings of the National Academy of Sciences·2025· 5 citedOpen Access
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Frequent Co-authors

George C. Schatz(9), Robert L. Letsinger(8), Robert C. Mucic(6), James J. Storhoff(6), Rongchao Jin(6), C. Shad Thaxton(4), David A. Giljohann(4), Abigail K. R. Lytton‐Jean(4), Robert Elghanian(3), Jwa‐Min Nam(3), Byeongdu Lee(3), Matthew R. Jones(3), Joshua I. Cutler(3), Jill E. Millstone(3), Nathaniel L. Rosi(2), T. Andrew Taton(2), Min Su Han(2), Gabriella S. Métraux(2), So‐Jung Park(2), Steven Weigand(2)