Christina Claus

Roche (Switzerland) — Switzerland

Medicine · Health Sciences

13h-index1.2kcitations59works4.42yr avg
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Research Topics

CAR-T cell therapy research(32), Monoclonal and Polyclonal Antibodies Research(30), Cancer Immunotherapy and Biomarkers(16), Radiopharmaceutical Chemistry and Applications(15), Peptidase Inhibition and Analysis(11)

Publications59 total

P329G-engager: a universal mix & match antibody-based adaptor platform for cancer immunotherapy
mAbs·2025Open Access
CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCB
Antibodies·2025Open Access
CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCB
Preprints.org·2025Open Access
CEA-4-1BBL: Design and Optimization of a Novel CEACAM5-Targeted 4-1BB Ligand Antibody Fusion Protein to Provide Costimulation in Cis in Combination with T Cell Bispecific Antibodies
Preprints.org·2025Open Access
Altered levels of angiogenin and tRNA-derived fragments associate with severe asthma
Scientific Reports·2025· 2 citedOpen Access
Abstract 640: Augmenting T-cell bispecific antibody therapy in AML through co-stimulatory agonists
Cancer Research·2025
4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models
Journal for ImmunoTherapy of Cancer·2025· 13 citedOpen Access
781 4–1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models
Regular and Young Investigator Award Abstracts·2024Open Access
Combining mathematical modeling, in vitro data and clinical target expression to support bispecific antibody binding affinity selection: a case example with FAP-4-1BBL
Frontiers in Pharmacology·2024· 1 citedOpen Access
Abstract 6709: P329G-Engager: A novel universal antibody-based adaptor platform for cancer immunotherapy
Cancer Research·2024
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy
Blood·2024· 32 citedOpen Access
A model‐based approach leveraging in vitro data to support dose selection from the outset: A framework for bispecific antibodies in immuno‐oncology
CPT Pharmacometrics & Systems Pharmacology·2023· 4 citedOpen Access
P1211: TUMOR-ACTIVATED LYMPH NODE FIBROBLASTS SUPPRESS T CELL FUNCTION IN DIFFUSE LARGE B CELL LYMPHOMA
HemaSphere·2023Open Access
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Journal of Clinical Investigation·2023· 48 citedOpen Access
Abstract 1100: 4-1BBL agonist targeted to fibroblast activation protein α synergizes with radiotherapy in murine breast tumor
Cancer Research·2023
Figure S4 from The PET-Tracer <sup>89</sup>Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2023Open Access
Figure S1 from The PET-Tracer <sup>89</sup>Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2023Open Access
Figure S5 from The PET-Tracer <sup>89</sup>Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2023Open Access
Figure S6 from The PET-Tracer <sup>89</sup>Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2023Open Access
Figure S5 from The PET-Tracer <sup>89</sup>Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2023Open Access
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Frequent Co-authors

Christian Klein(34), Pablo Umaña(33), Marina Bacac(26), Claudia Ferrara(24), Johannes Sam(24), Valeria Nicolini(19), Maria Amann(17), Christoph M. Griessinger(13), Alessandro Mascioni(13), Michael Torgov(13), Ian A. Wilson(13), Jean Tessier(13), Peter Brünker(12), Marine Richard(12), Tove Olafsen(11), Ziyue Karen Jiang(11), Charles Zamilpa(11), Jason M. Romero(11), Filippo Marchioni(11), Daulet Satpayev(11)