Bennett Van Houten

University of Pittsburgh — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

81h-index22.2kcitations372works2.62yr avg
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Research Topics

DNA Repair Mechanisms(144), Mitochondrial Function and Pathology(75), DNA and Nucleic Acid Chemistry(68), Bacterial Genetics and Biotechnology(38), Cancer, Hypoxia, and Metabolism(34)

Publications370 total

PARP1 recruits SPRTN to DNA-protein crosslinks through a conserved poly-ADP-ribose binding domain
2026Open Access
Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks
Nature Communications·2025· 2 citedOpen Access
The zinc finger of DNA ligase 3α binds to nucleosomes via an arginine anchor
Nature Communications·2025· 1 citedOpen Access
Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease
2025Open Access
Nucleosome unwrapping and PARP1 allostery drive affinities for chromatin and DNA breaks
2025Open Access
SON-dependent nuclear speckle rehabilitation alleviates proteinopathies
Nature Communications·2025· 4 citedOpen Access
Editors’ note Penny Jeggo and Bennett Van Houten
DNA repair·2025
The zinc finger of DNA Ligase 3α binds to nucleosomes via an arginine anchor
2025Open Access
Editorial
DNA repair·2025
Unlocking transcription-coupled DNA repair with the STK19 key
Molecular Cell·2024· 2 cited
Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Nature Communications·2024· 9 citedOpen Access
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
Nature Communications·2024· 8 citedOpen Access
The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA
2024· 2 citedOpen Access
Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glycosylase 1
DNA repair·2024· 10 citedOpen Access
Utilizing nuclear extracts to characterize protein: DNA interactions at the single molecule level
Methods in enzymology on CD-ROM/Methods in enzymology·2024· 1 citedOpen Access
BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and lesions
Nucleic Acids Research·2023· 16 citedOpen Access
Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glycosylase 1
2023· 1 citedOpen Access
Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
2023· 8 citedOpen Access
Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity
Proceedings of the National Academy of Sciences·2023· 8 citedOpen Access
UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct Role in Base Excision Repair
International Journal of Molecular Sciences·2023· 2 citedOpen Access
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Frequent Co-authors

Janine H. Santos(9), Michelle Barbi de Moura(6), Joel N. Meyer(5), Bhaskar S. Mandavilli(4), Deborah L. Croteau(4), Caroline Kisker(4), Michael T. Lotze(3), Wei Qian(3), Charleen T. Chu(3), F. Michael Yakes(2), Scott W. Ballinger(2), Amy M. Furda(2), J.J. Truglio(2), Daolin Tang(2), Rui Kang(2), Kristen M. Livesey(2), Timothy R. Billiar(2), Herbert J. Zeh(2), Astrid C. Haugen(2), Robert W. Sobol(2)