Ramnik J. Xavier

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

184h-index184.4kcitations998works16.82yr avg
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Research Topics

Gut microbiota and health(223), Inflammatory Bowel Disease(220), Microscopic Colitis(98), Autophagy in Disease and Therapy(79), Immune Cell Function and Interaction(73)

Publications958 total

Abstract PR011: Early-onset colorectal cancer is characterized by transcriptional changes indicating increased epithelial-mesenchymal transition and metastatic potential
Clinical Cancer Research·2025
Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity
Nature Communications·2025· 2 citedOpen Access
Population-scale multiome immune cell atlas reveals complex disease drivers
2025Open Access
Allosteric modulation of the solute carrier transporter SLC39A8 potentiates manganese and cadmium uptake
Journal of Clinical Investigation·2025Open Access
Human immunodeficiency virus and antiretroviral therapies exert distinct influences across diverse gut microbiomes
Nature Microbiology·2025· 1 cited
Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation
Science·2025· 1 cited
Industrialization drives convergent microbial and physiological shifts in the human metaorganism
2025· 2 citedOpen Access
Convergent genomic responses of human gut bacteria to variations in industrialization
2025· 2 citedOpen Access
Delayed Remission With Advanced Therapies Is Not Associated With Worse 1-Year Outcomes in Inflammatory Bowel Disease
The American Journal of Gastroenterology·2025
A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity
2025Open Access
Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation
Proceedings of the National Academy of Sciences·2025Open Access
Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation
The Journal of Experimental Medicine·2025
Elucidating the role of <i>Campylobacter concisus</i> –derived indole metabolites in gut inflammation and immune modulation
Proceedings of the National Academy of Sciences·2025· 5 citedOpen Access
Microbial Adaptation in Healthy Ageing: Insights from Age-associated Structural Variation in the Human Gut Microbiome
2025Open Access
<i>Eggerthella lenta</i> Produces a Cryptic Pro-inflammatory Lipid
Journal of the American Chemical Society·2025· 1 citedOpen Access
An International Multicenter Study of Native and Immigrant South Asian Crohn’s Disease
Clinical Gastroenterology and Hepatology·2025· 2 cited
Single-cell and spatial transcriptomics of stricturing Crohn’s disease highlights a fibrosis-associated network
Nature Genetics·2025· 17 citedOpen Access
Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance
Frontiers in Microbiomes·2025· 1 citedOpen Access
Intelectin-2 is a broad-spectrum antimicrobial lectin
2025
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway
Cell Host & Microbe·2025· 12 cited
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Frequent Co-authors

Curtis Huttenhower(13), Cisca Wijmenga(11), Hera Vlamakis(11), Dirk Gevers(10), Mihai G. Netea(10), Leo A. B. Joosten(9), Tommi Vatanen(9), Eric A. Franzosa(8), Aylwin Ng(6), Hendrik G. Stunnenberg(6), Rinse K. Weersma(5), Clary B. Clish(5), Luke O'neill(5), Melanie Schirmer(5), J.W.M. van der Meer(5), Alexandra Zhernakova(5), Jingyuan Fu(5), Dermot McGovern(4), L. Philip Schumm(4), Subra Kugathasan(4)