Mahmoud S. Alghamri

University of Michigan — United States

Medicine · Health Sciences

19h-index1.5kcitations57works0.82yr avg
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Research Topics

Glioma Diagnosis and Treatment(25), Immune cells in cancer(13), Virus-based gene therapy research(10), Immunotherapy and Immune Responses(8), Epigenetics and DNA Methylation(7)

Publications57 total

Reprogramming the Immune Suppressive Tumor Microenvironment in Glioma Enhances the Efficacy of Immune-Mediated Gene Therapy
2025
Autophagy Upregulation in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma Uncovers a Novel Therapeutic Target
2025Open Access
Peripheral blood mononuclear cell (PBMC)- based functional evaluation of human T cell response to suppressive cells and immune-oncology therapeutics
Methods in cell biology·2025
TMIC-79. IDH1-R132H REWIRES AUTOPHAGY IN THE GLIOMA MICROENVIRONMENT TO FACILITATE TUMOR PROGRESSION AND RESPONSE TO RADIATION
Neuro-Oncology·2024· 1 citedOpen Access
Epigenetic Reprogramming of Autophagy Leads to Uncovering a Novel Therapeutic Target for Mutant IDH1 Astrocytomas
2024· 3 citedOpen Access
The magic of MAGI‐1: A scaffolding protein with multi signalosomes and functional plasticity
Biology of the Cell·2023· 2 citedOpen Access
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas
2023· 6 citedOpen Access
Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade
Nature Communications·2023· 39 citedOpen Access
Impact of epigenetic reprogramming on antitumor immune responses in glioma
Journal of Clinical Investigation·2023· 60 citedOpen Access
H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models
Journal of Clinical Investigation·2022· 82 citedOpen Access
Systemic Delivery of an Adjuvant CXCR4–CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy
ACS Nano·2022· 133 citedOpen Access
Murine brain tumor microenvironment immunophenotyping using mass cytometry
STAR Protocols·2022· 2 citedOpen Access
The magic of MAGI‐1: A scaffolding protein with multi signalosomes and functional plasticity
Biology of the Cell·2022· 7 citedOpen Access
T lymphocytes as dynamic regulators of glioma pathobiology
Neuro-Oncology·2022· 50 citedOpen Access
The Coxsackievirus and Adenovirus Receptor Has a Short Half-Life in Epithelial Cells
Pathogens·2022· 1 citedOpen Access
G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy
Science Advances·2021· 87 citedOpen Access
Systemic delivery of a CXCR4-CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy
2021· 1 citedOpen Access
Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
Frontiers in Oncology·2021· 23 citedOpen Access
Targeting Neuroinflammation in Brain Cancer: Uncovering Mechanisms, Pharmacological Targets, and Neuropharmaceutical Developments
Frontiers in Pharmacology·2021· 84 citedOpen Access
MAGI-1 PDZ2 Domain Blockade Averts Adenovirus Infection via Enhanced Proteolysis of the Apical Coxsackievirus and Adenovirus Receptor
Journal of Virology·2021· 6 citedOpen Access
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Frequent Co-authors

Pedro R. Löwenstein(33), María G. Castro(31), Felipe J. Núñez(23), Padma Kadiyala(23), Stephen V. Carney(18), María Belén Garcia-Fabiani(14), Santiago Haase(13), Neha Kamran(12), Brandon L. McClellan(12), Andrea Comba(12), Ayman Taher(11), Syed Mohd Faisal(11), Kaushik Banerjee(10), Marta Edwards(8), Rohit Thalla(8), Anzar Mujeeb(7), Anna Schwendeman(7), Tingting Qin(6), Maureen A. Sartor(6), Dolores Hambardzumyan(6)