Jason Munguia

University of California, San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index773citations14works0.72yr avg
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Research Topics

Antibiotic Resistance in Bacteria(5), Antimicrobial Peptides and Activities(3), Protein Structure and Dynamics(2), HIV Research and Treatment(2), Bacterial Genetics and Biotechnology(2)

Publications14 total

Abstract 5720: Novel selective FEN1 nuclease inhibitor shows synergy with PARP-targeting drugs
Cancer Research·2025· 1 cited
Anesthetic choice impacts mortality and bacterial clearance in a murine experimental pneumonia model
BMC Infectious Diseases·2025· 1 citedOpen Access
Abstract 7148: Small molecule inhibitor of FEN1 nuclease utilizing a novel metal-binding pharmacophore synergizes with inhibitors of USP1, PARP, PARG and ATR
Cancer Research·2024
Docking simulation and antibiotic discovery targeting the MlaC protein in Gram‐negative bacteria
Chemical Biology & Drug Design·2018· 6 cited
The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance
Journal of Molecular Medicine·2017· 45 citedOpen Access
Pharmacological Targeting of the Host–Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs
Trends in Pharmacological Sciences·2017· 131 citedOpen Access
Classical β-Lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin against Acinetobacter baumannii
Antimicrobial Agents and Chemotherapy·2016· 21 citedOpen Access
Molecular dynamic study of MlaC protein in Gram‐negative bacteria: conformational flexibility, solvent effect and protein‐phospholipid binding
Protein Science·2016· 34 citedOpen Access
New Approaches to Sensitize Multidrug-Resistant Gram-Negative Bacterial Pathogens to Host Innate Immune Clearance
eScholarship (California Digital Library)·2016Open Access
Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens
EBioMedicine·2015· 282 citedOpen Access
Salinipyrone and Pacificanone Are Biosynthetic By‐products of the Rosamicin Polyketide Synthase
ChemBioChem·2015· 27 cited
HIV-1 Vpu Protein Antagonizes Innate Restriction Factor BST-2 via Lipid-embedded Helix-Helix Interactions
Journal of Biological Chemistry·2011· 103 citedOpen Access
Structure of BST-2/Tetherin Transmembrane Domain
Journal of Back and Musculoskeletal Rehabilitation·2011
Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu
Journal of Virology·2010· 122 citedOpen Access

Frequent Co-authors

Victor Nizet(8), Joshua Olson(4), Andrey Tokarev(3), John Guatelli(3), Poochit Nonejuie(2), George Sakoulas(2), Mark Skasko(2), Ye Tian(2), Autumn Ruiz(2), Edward B. Stephens(2), Stanley J. Opella(2), Ingrid Cornax(2), Joseph Pogliano(2), Yu‐ming M. Huang(2), Yinglong Miao(2), J. Andrew McCammon(2), Sanjay Agarwalla(2), Dave Martin(2), Junhua Fan(2), Dave Lonergan(2)