Peter Heutink

Allen Institute for Brain Science — United States

Medicine · Health Sciences

111h-index63.5kcitations714works10.12yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(123), Neurological diseases and metabolism(78), Alzheimer's disease research and treatments(72), Amyotrophic Lateral Sclerosis Research(62), Genetic Associations and Epidemiology(44)

Publications683 total

The Alzheimer’s disease risk genes MS4A4A and MS4A6A cooperate to negatively regulate TREM2 and microglia states
Neuron·2025
Chr:17q21.31 locus risk haplotype H1 susceptibility to ferroptosis is mediated by endolysosomal pathway
Cell Death and Disease·2025Open Access
Integrative analysis of pooled CRISPR screens provide functional insights into AD GWAS risk genes
2025· 1 citedOpen Access
The Global Landscape of Genetic Variation in Parkinson’s disease: Multi-Ancestry Insights into Established Disease Genes and their Translational Relevance
2025· 4 citedOpen Access
DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal Lobar degeneration genetic risk-associated loci
Acta Neuropathologica Communications·2025Open Access
Piccolo Regulates Secretion of the Extracellular Matrix Components Brevican and Tenascin R from Astrocytes to Drive Synapse Formation: Implications for Pontocerebellar Hypoplasia Type 3 (PCH3)
2025Open Access
The Insertion of an ATTTC Repeat in an Alu Element Hyperactivates a Primate-Specific Neurodevelopmental Enhancer in Spinocerebellar Ataxia Type 37
2025· 1 citedOpen Access
A role for astrocytic miR-129-5p in frontotemporal dementia
Translational Psychiatry·2025· 5 citedOpen Access
Polygenic scores for disease risk are not associated with clinical outcomes in Parkinson’s disease
2025· 1 citedOpen Access
DNA methylation as a contributor to dysregulation of <i>STX6</i> and other frontotemporal lobar degeneration genetic risk-associated loci
2025· 1 citedOpen Access
The Alzheimer's Disease Risk Genes MS4A4A and MS4A6A Cooperate to Negatively Regulate TREM2 and Microglia States
SSRN Electronic Journal·2025Open Access
Arrayed CRISPR libraries for the genome-wide activation, deletion and silencing of human protein-coding genes
Nature Biomedical Engineering·2024· 22 citedOpen Access
The Alzheimer’s Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states
2024· 5 citedOpen Access
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2
npj Parkinson s Disease·2024· 1 citedOpen Access
Dopamine Pathway and Parkinson's Risk Variants Are Associated with Levodopa‐Induced Dyskinesia
Movement Disorders·2024· 6 citedOpen Access
Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale
Movement Disorders·2024· 8 citedOpen Access
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS
Nature Medicine·2024· 162 citedOpen Access
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors <i>USF2</i> and <i>ONECUT2</i>
2024Open Access
A role for astrocytic miR-129-5p in Frontotemporal Dementia
2024· 3 citedOpen Access
Understanding monogenic Parkinson's disease at a global scale
2024· 3 citedOpen Access
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Frequent Co-authors

John Hardy(18), Alexis Brice(16), John C. van Swieten(14), J. Raphael Gibbs(13), Andrew Singleton(11), Ben A. Oostra(11), Jean‐Christophe Corvol(11), Joshua Shulman(11), Suzanne Lesage(10), Thomas Gasser(10), Huw R. Morris(9), Javier Simón‐Sánchez(8), Cornelia M. van Duijn(8), Manu Sharma(8), Nicholas Wood(8), Dena G. Hernandez(8), Marijke Joosse(7), Mike A. Nalls(7), Claudia Schulte(7), María Martínez(7)