Safaa Yehia Eid

Umm al-Qura University — Saudi Arabia

Medicine · Health Sciences

17h-index962citations36works3.82yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(7), Natural product bioactivities and synthesis(5), Drug-Induced Hepatotoxicity and Protection(5), Phytochemistry and Biological Activities(5), Essential Oils and Antimicrobial Activity(4)

Publications35 total

Protective effects of oral pharmaceutical solution of fucoxanthin against paracetamol-induced liver injury: modulation of drug-metabolizing enzymes, oxidative stress, and apoptotic pathways in rats
Drug Development and Industrial Pharmacy·2025
Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters
Frontiers in Pharmacology·2024· 2 citedOpen Access
Myricetin inhibits CYP3A4, GST, and MRP1 in hepatic cancer cells
Journal of Umm Al-Qura University for Applied Sciences·2024Open Access
Doxorubicin-sanguinarine nanoparticles: formulation and evaluation of breast cancer cell apoptosis and cell cycle
Drug Development and Industrial Pharmacy·2024· 13 cited
Antioxidative and Anti-Inflammatory Protective Effects of Fucoxanthin against Paracetamol-Induced Hepatotoxicity in Rats
Marine Drugs·2023· 21 citedOpen Access
Vitamin D and calcium co-therapy mitigates pre-established cadmium nephropathy by regulating renal calcium homeostatic molecules and improving anti-oxidative and anti-inflammatory activities in rat
Journal of Trace Elements in Medicine and Biology·2023· 12 cited
Cymbopogon citratus and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters
Molecules·2023· 12 citedOpen Access
Patterns of acute poisoning for children during outbreak of Corona virus in Makkah region Saudi Arabia
Frontiers in Pediatrics·2023· 9 citedOpen Access
Liver Injury in Favipiravir-Treated COVID-19 Patients: Retrospective Single-Center Cohort Study
Tropical Medicine and Infectious Disease·2023· 4 citedOpen Access
The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study
Complementary Therapies in Medicine·2023· 9 citedOpen Access
In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network
Cancers·2022· 37 citedOpen Access
Short-Term Treatment of Metformin and Glipizide on Oxidative Stress, Lipid Profile and Renal Function in a Rat Model with Diabetes Mellitus
Applied Sciences·2022· 7 citedOpen Access
Metformin and Calcitriol Enhance 5-Fluorouracil Tumoricidal Effects in Colon Cancer By Modulating The PI3K/Akt/PTEN/mTOR Network
Research Square (Research Square)·2022Open Access
Sage, Salvia officinalis L., Constituents, Hepatoprotective Activity, and Cytotoxicity Evaluations of the Essential Oils Obtained from Fresh and Differently Timed Dried Herbs: A Comparative Analysis
Molecules·2021· 45 citedOpen Access
Multiple Molecular Mechanisms to Overcome Multidrug Resistance in Cancer by Natural Secondary Metabolites
Frontiers in Pharmacology·2021· 41 citedOpen Access
BTK targeting suppresses inflammatory genes and ameliorates insulin resistance
European Cytokine Network·2020· 11 cited
Chrysanthemum indicum and Chrysanthemum morifolium: Chemical Composition of Their Essential Oils and Their Potential Use as Natural Preservatives with Antimicrobial and Antioxidant Activities
Foods·2020· 97 citedOpen Access
Abstract 6561: Mathematical analysis for the combinatorial cytotoxic properties of the standardized extract of <i>Annona cherimola</i> or <i>Solanum nigrum</i> with 5-FU against head and neck cancer cells
Cancer Research·2020
The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes
Phytomedicine·2020· 48 cited
Evaluation of the Diagnostic and Predicative Values of 8-Iso-Prostaglandin F2α as a Biomarker of Breast Cancer
Oncology Research and Treatment·2020· 12 cited
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Frequent Co-authors

Mahmoud Zaki El-Readi(30), Mohammad Althubiti(14), Michaël Wink(13), Riyad A. Almaimani(9), Bassem Refaat(9), Mohamed L. Ashour(6), Essam Eldin Mohamed Nour Eldin(5), Shakir Idris(5), Sameer H. Fatani(4), Ahmed A. H. Abdellatif(4), Hiba S. Al-Amodi(4), Akhmed Aslam(4), Mohamed E. Elzubier(4), Jawwad Ahmad(3), Mohamed El‐Boshy(3), Hussain A. Almasmoum(3), Mazen M. Ghaith(3), Abdullah R. Alzahrani(3), Saeed Alghamdi(3), Nahla Ayoub(3)